预测英国男男性行为者的PrEP可接受性和自我效能:身份弹性、科学不信任和污名的作用。

IF 2.8 3区 医学 Q2 INFECTIOUS DISEASES
HIV Medicine Pub Date : 2025-02-27 DOI:10.1111/hiv.13768
Anthony J. Gifford, Rusi Jaspal, Bethany A. Jones, Daragh T. McDermott
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引用次数: 0

摘要

暴露前预防(PrEP)是用于预防艾滋病毒传播的药物。在英国,艾滋病毒预防需求增加的人群(例如男男性行为者[MSM])有资格获得免费的PrEP。然而,艾滋病毒监测报告表明,该药的吸收停滞不前,同时艾滋病毒感染率也在上升。因此,需要进行社会心理研究,以探索PrEP接受的社会障碍。本研究旨在探讨身份弹性(即保持积极和稳定的自我意识的能力)在PrEP使用中的预测作用。我们假设PrEP自我效能感(即相信自己有能力采取PrEP)会被PrEP可接受性积极预测。我们还假设身份价值和身份连续性(身份弹性的组成部分)与PrEP可接受性和PrEP自我效能有关。对科学的不信任、PrEP的污名化和对艾滋病毒的感知风险将调解这些问题。方法:在2023年6月至9月期间,共有500名出生时被指定为男性、年龄≥18岁、未感染艾滋病毒的男男性行为者参加了一项在线横断面心理测量学研究。参与者必须居住在英国,但可以是PrEP使用者或非使用者。使用结构方程模型来探索最适合的模型来检验假设。结果:参与者年龄在18-73岁之间(平均35.61岁,标准差[SD] 9.95),主要为白人(91.2%),本科及以上学历(70.9%),未使用PrEP(58.2%)。模型拟合满意:χ2 = 4.51,自由度= 3,p值= 0.209,比较拟合指数0.997,Tucker Lewis指数0.972,近似均方根0.032,标准化均方根残差0.011。身份价值与PrEP自我效能呈正相关。认同价值与PrEP可接受性和PrEP自我效能感有间接关系。认同价值与PrEP可接受性的正相关通过对科学的不信任程度降低和PrEP污名化程度降低而介导,但不通过感知HIV风险介导。结论:结果表明,采取PrEP的决定与身份价值(即自尊、自我效能感和独特性)的构建有关,而不仅仅是基于风险的评估。获取和使用预防措施的原因可能不再是由于固有的艾滋病毒感染风险。当试图增加PrEP的吸收时,解决身份弹性的特定部分可能是有益的。例如,治疗干预(如咨询)可包括改善积极的性身份和自尊的干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Predicting PrEP acceptability and self-efficacy among men who have sex with men in the UK: The roles of identity resilience, science mistrust, and stigma

Predicting PrEP acceptability and self-efficacy among men who have sex with men in the UK: The roles of identity resilience, science mistrust, and stigma

Introduction

Pre-exposure prophylaxis (PrEP) is medication used to prevent the spread of HIV. Populations with increased need of HIV prevention (e.g., men who have sex with men [MSM]) are eligible for free PrEP in the UK. However, HIV surveillance reports indicate stagnated uptake of the drug, alongside increasing rates of HIV acquisition. As such, psychosocial research is needed to explore the social barriers to PrEP uptake. This study aimed to explore the role of identity resilience (i.e., ability to maintain a positive and stable sense of self) as a predictor for PrEP usage. We hypothesized that PrEP self-efficacy (i.e., belief in one's ability to take PrEP) would be positively predicted by PrEP acceptability. We also hypothesized that identity worth and identity continuity (components of identity resilience) would be associated with PrEP acceptability and PrEP self-efficacy. These would be mediated by mistrust in science, PrEP stigma, and perceived risk of HIV.

Methods

In total, 500 MSM who were assigned male at birth, were aged ≥18 years, and did not have HIV participated in an online cross-sectional, psychometric study between June and September 2023. Participants had to be based in the UK but could either be PrEP users or non-users. Structural equation modelling was used to explore a model of best fit to test the hypotheses.

Results

Participants were aged 18–73 years (mean 35.61, standard deviation [SD] 9.95), mostly (91.2%) white, educated to an undergraduate level or above (70.9%), and non-users of PrEP (58.2%). Model fit was satisfactory: χ2 = 4.51, degrees of freedom = 3, p-value = 0.209, comparative fit index 0.997, Tucker Lewis Index 0.972, root mean square of approximation 0.032, and standardized root mean square residual 0.011. Identity worth was positively associated with PrEP self-efficacy. Identity worth was indirectly associated with PrEP acceptability and PrEP self-efficacy. The positive association of identity worth and PrEP acceptability was mediated through lower mistrust of science and lower PrEP stigma but not perceived risk of HIV.

Conclusions

Results indicate that the decision to take PrEP is associated with the constructs of identity worth (i.e., self-esteem, self-efficacy, and distinctiveness) rather than risk-based appraisals alone. The reasons for accessing and using PrEP may no longer be motivated by an inherent perceived risk of HIV acquisition. When trying to increase PrEP uptake, addressing specific parts of identity resilience may be beneficial. For example, therapeutic interventions (e.g., counselling) could include interventions to improve positive sexual identities and self-esteem.

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来源期刊
HIV Medicine
HIV Medicine 医学-传染病学
CiteScore
5.10
自引率
10.00%
发文量
167
审稿时长
6-12 weeks
期刊介绍: HIV Medicine aims to provide an alternative outlet for publication of international research papers in the field of HIV Medicine, embracing clinical, pharmocological, epidemiological, ethical, preclinical and in vitro studies. In addition, the journal will commission reviews and other feature articles. It will focus on evidence-based medicine as the mainstay of successful management of HIV and AIDS. The journal is specifically aimed at researchers and clinicians with responsibility for treating HIV seropositive patients.
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