Yang Su, Ran Ji, Xiaoyan Zheng, Yan Jia, Hao Zhu, Chaoliang Li, Zheng Yu, Manjia Zhu, Siyi Yu, Xiaoping Tian, Jie Yang
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The surface under the cumulative ranking (SUCRA) was applied to rank the acupuncture-related therapies for each outcome.</p><h3>Results</h3><p>Twenty-three randomized controlled trials (RCTs) involving one thousand five hundred forty-five patients were included in the network meta-analysis. Ear electroacupuncture (SUCRA = 83.0%), needle warming moxibustion with Modified Neiyi Zhitong Formula (SUCRA = 80.6%), and auricular needle-embedding (SUCRA = 79.6%) demonstrated a statistically significant reduction in comprehensive symptoms compared to the control group. Studies have shown that body electroacupuncture (OR = 4.33, 95% CI 1.20–15.61), acupoint catgut (OR = 4.32, 95% CI 1.08–17.25), and auricular needle-embedding (OR = 7.56, 95% CI 1.89–30.28) are statistically significantly more effective than conventional treatment.</p><h3>Conclusion</h3><p>The results of this analysis suggest that acupuncture-related therapies are effective in managing symptomatic endometriosis. 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引用次数: 0
摘要
目的：比较不同针灸疗法结合药物疗法治疗症状性子宫内膜异位症的有效性和安全性：比较不同针灸疗法联合药物疗法治疗症状性子宫内膜异位症的有效性和安全性：方法：从开始到2023年5月1日，在8个数据库（中国生物医学文献服务系统、中国国家知识基础设施、万方数据知识服务平台、中国科技期刊数据库、PubMed、Embase、Cochrane图书馆和Web of Science）中采用预先定义的检索策略。采用 Cochrane 偏倚风险评估工具对纳入的研究进行了方法学质量评估。结果显示，23 项随机对照试验（RFID）的研究结果显示，针灸疗法的疗效明显优于其他疗法：网络荟萃分析纳入了 23 项随机对照试验（RCT），涉及 1,545 名患者。与对照组相比，耳部电针（SUCRA = 83.0%）、针刺温灸加改良内服智通方（SUCRA = 80.6%）和耳穴针刺（SUCRA = 79.6%）在统计学上显著减轻了综合症状。研究表明，体针（OR = 4.33，95% CI 1.20-15.61）、穴位埋线（OR = 4.32，95% CI 1.08-17.25）和耳针埋线（OR = 7.56，95% CI 1.89-30.28）在统计学上明显比常规治疗有效：结论：分析结果表明，针灸相关疗法可有效治疗无症状子宫内膜异位症。试验注册：我们的研究方案已在系统综述和荟萃分析方案国际注册平台（INPLASY）注册；注册号：INPLASY202380077。
Efficacy and safety of acupuncture-related therapies in symptomatic endometriosis: a systematic review and network meta-analysis
Objective
To compare the effectiveness and safety of different acupuncture-related therapies combined with pharmacotherapies for treating symptomatic endometriosis.
Methods
A pre-defined search strategy was conducted across eight databases (Chinese Biomedical Literature Service System, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, China Science and Technology Journal Database, PubMed, Embase, Cochrane Library, and Web of Science) from inception to May 1, 2023. The included studies were evaluated for methodological quality using the Cochrane risk of bias assessment tool. The surface under the cumulative ranking (SUCRA) was applied to rank the acupuncture-related therapies for each outcome.
Results
Twenty-three randomized controlled trials (RCTs) involving one thousand five hundred forty-five patients were included in the network meta-analysis. Ear electroacupuncture (SUCRA = 83.0%), needle warming moxibustion with Modified Neiyi Zhitong Formula (SUCRA = 80.6%), and auricular needle-embedding (SUCRA = 79.6%) demonstrated a statistically significant reduction in comprehensive symptoms compared to the control group. Studies have shown that body electroacupuncture (OR = 4.33, 95% CI 1.20–15.61), acupoint catgut (OR = 4.32, 95% CI 1.08–17.25), and auricular needle-embedding (OR = 7.56, 95% CI 1.89–30.28) are statistically significantly more effective than conventional treatment.
Conclusion
The results of this analysis suggest that acupuncture-related therapies are effective in managing symptomatic endometriosis. Further high-quality randomized controlled trials are warranted to explore their efficacy and safety in greater depth.
Trial registration
Our study protocol was registered with the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY); registration number: INPLASY202380077.
期刊介绍：
Founded in 1870 as "Archiv für Gynaekologie", Archives of Gynecology and Obstetrics has a long and outstanding tradition. Since 1922 the journal has been the Organ of the Deutsche Gesellschaft für Gynäkologie und Geburtshilfe. "The Archives of Gynecology and Obstetrics" is circulated in over 40 countries world wide and is indexed in "PubMed/Medline" and "Science Citation Index Expanded/Journal Citation Report".
The journal publishes invited and submitted reviews; peer-reviewed original articles about clinical topics and basic research as well as news and views and guidelines and position statements from all sub-specialties in gynecology and obstetrics.
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