通过 C-S 和 C-H 键活化，钯催化α-芳基噻蒽盐与亚磺酰基锍的芳基化反应。

IF 3.3 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - An Asian Journal Pub Date : 2025-02-27 DOI:10.1002/asia.202401873

Prof. Qing-Dong Wang, Xue Chen, Yuan-Shuai Wu, Prof. Chengping Miao, Prof. Jin-Ming Yang, Prof. Zhi-Liang Shen

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引用次数: 0

摘要

通过钯催化亚砜鎓化物与芳基硫鎓盐的α-芳基芳化反应，以中高收率合成了多种α-芳基α-羰基亚砜鎓化物。通过C-S键和C-H键功能化反应进行顺利，具有广泛的底物范围和对各种官能团的良好相容性。此外，还可实现规模化合成，并可实现以简单芳烃为前驱体的一锅法合成芳基硫鎓盐。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Palladium–Catalyzed α-Arylation of Sulfoxonium Ylides with Aryl Thianthrenium Salts via C−S and C−H Bond Activation

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Palladium–Catalyzed α-Arylation of Sulfoxonium Ylides with Aryl Thianthrenium Salts via C−S and C−H Bond Activation

Diverse α-aryl α-carbonyl sulfoxonium ylides were efficiently synthesized in yields ranging from moderate to high via a palladium-catalyzed α-arylation of sulfoxonium ylides with aryl thianthrenium salts. The reactions proceeded smoothly via C−S and C−H bond functionalization, exhibiting broad substrate scope and good compatibility to various functionalities. In addition, the scale-up synthesis could be achieved, and the one-pot protocol commencing from the use of simple arene as the precursor of aryl thianthrenium salt could also be accomplished.

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来源期刊

Chemistry - An Asian Journal 化学-化学综合

CiteScore

7.00

自引率

2.40%

发文量

535

审稿时长

1.3 months

期刊介绍： Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics. Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews. A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal. Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).