骨盆骨折出血的威胁:临床医生寻求基于生物医学Mg植入物的新解决方案

IF 15.8 1区 材料科学 Q1 METALLURGY & METALLURGICAL ENGINEERING
Qinghui Han, Xiaonong Zhang, Wenhui Wang, Kaiyang Wang, Tao Wang
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引用次数: 0

摘要

生物可降解镁(Mg)材料由于其可降解性和优异的机械性能,在创伤护理中具有显著的优势。本研究报道了可降解Mg夹在骨盆骨折损伤控制手术中的首次成功应用,解决了与严重出血和高死亡率(30 - 70%)相关的挑战。一例57岁男性骨盆骨折伴外伤性休克患者行Mg夹切开复位内固定。在六个月的随访中,影像学证实骨折愈合,夹退化,无再出血或感染迹象,突出了其在精确出血控制方面的有效性。与传统的钛夹不同,Mg夹会随着时间的推移而降解,无需移除并降低感染风险。这种创新的方法将Mg夹与传统的纱布包装相结合,为治疗盆腔创伤提供了更有效、更安全的选择。未来需要大规模的临床试验来验证这些发现,并将镁夹作为骨盆骨折治疗的全球标准。它们的便携性和功能性为推进紧急创伤护理带来了希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The threat of hemorrhage from pelvic fractures: Clinicians seeking new solutions based on biomedical Mg implant

The threat of hemorrhage from pelvic fractures: Clinicians seeking new solutions based on biomedical Mg implant
Biodegradable magnesium (Mg) materials offer significant advantages in trauma care due to their degradable nature and superior mechanical properties. This study reports the first successful use of degradable Mg clips in damage control surgery for pelvic fractures, addressing challenges associated with severe hemorrhage and high mortality rates (30–70 %). A 57-year-old male patient with pelvic fractures and traumatic shock underwent open reduction and internal fixation with Mg clips. At a six-month follow-up, imaging confirmed fracture healing, clip degradation, and no signs of rebleeding or infection, highlighting their effectiveness in precise hemorrhage control. Unlike traditional titanium clips, Mg clips degrade over time, eliminating the need for removal and reducing infection risks. This innovative approach combines Mg clips with conventional gauze packing, offering a more effective and safer alternative for managing pelvic trauma. Future large-scale clinical trials are necessary to validate these findings and establish Mg clips as a global standard for pelvic fracture treatment. Their portability and functionality hold promise for advancing emergency trauma care.
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来源期刊
Journal of Magnesium and Alloys
Journal of Magnesium and Alloys Engineering-Mechanics of Materials
CiteScore
20.20
自引率
14.80%
发文量
52
审稿时长
59 days
期刊介绍: The Journal of Magnesium and Alloys serves as a global platform for both theoretical and experimental studies in magnesium science and engineering. It welcomes submissions investigating various scientific and engineering factors impacting the metallurgy, processing, microstructure, properties, and applications of magnesium and alloys. The journal covers all aspects of magnesium and alloy research, including raw materials, alloy casting, extrusion and deformation, corrosion and surface treatment, joining and machining, simulation and modeling, microstructure evolution and mechanical properties, new alloy development, magnesium-based composites, bio-materials and energy materials, applications, and recycling.
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