Qinghui Han, Xiaonong Zhang, Wenhui Wang, Kaiyang Wang, Tao Wang
{"title":"骨盆骨折出血的威胁:临床医生寻求基于生物医学Mg植入物的新解决方案","authors":"Qinghui Han, Xiaonong Zhang, Wenhui Wang, Kaiyang Wang, Tao Wang","doi":"10.1016/j.jma.2025.02.007","DOIUrl":null,"url":null,"abstract":"Biodegradable magnesium (Mg) materials offer significant advantages in trauma care due to their degradable nature and superior mechanical properties. This study reports the first successful use of degradable Mg clips in damage control surgery for pelvic fractures, addressing challenges associated with severe hemorrhage and high mortality rates (30–70 %). A 57-year-old male patient with pelvic fractures and traumatic shock underwent open reduction and internal fixation with Mg clips. At a six-month follow-up, imaging confirmed fracture healing, clip degradation, and no signs of rebleeding or infection, highlighting their effectiveness in precise hemorrhage control. Unlike traditional titanium clips, Mg clips degrade over time, eliminating the need for removal and reducing infection risks. This innovative approach combines Mg clips with conventional gauze packing, offering a more effective and safer alternative for managing pelvic trauma. Future large-scale clinical trials are necessary to validate these findings and establish Mg clips as a global standard for pelvic fracture treatment. Their portability and functionality hold promise for advancing emergency trauma care.","PeriodicalId":16214,"journal":{"name":"Journal of Magnesium and Alloys","volume":"85 1","pages":""},"PeriodicalIF":15.8000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The threat of hemorrhage from pelvic fractures: Clinicians seeking new solutions based on biomedical Mg implant\",\"authors\":\"Qinghui Han, Xiaonong Zhang, Wenhui Wang, Kaiyang Wang, Tao Wang\",\"doi\":\"10.1016/j.jma.2025.02.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Biodegradable magnesium (Mg) materials offer significant advantages in trauma care due to their degradable nature and superior mechanical properties. This study reports the first successful use of degradable Mg clips in damage control surgery for pelvic fractures, addressing challenges associated with severe hemorrhage and high mortality rates (30–70 %). A 57-year-old male patient with pelvic fractures and traumatic shock underwent open reduction and internal fixation with Mg clips. At a six-month follow-up, imaging confirmed fracture healing, clip degradation, and no signs of rebleeding or infection, highlighting their effectiveness in precise hemorrhage control. Unlike traditional titanium clips, Mg clips degrade over time, eliminating the need for removal and reducing infection risks. This innovative approach combines Mg clips with conventional gauze packing, offering a more effective and safer alternative for managing pelvic trauma. Future large-scale clinical trials are necessary to validate these findings and establish Mg clips as a global standard for pelvic fracture treatment. Their portability and functionality hold promise for advancing emergency trauma care.\",\"PeriodicalId\":16214,\"journal\":{\"name\":\"Journal of Magnesium and Alloys\",\"volume\":\"85 1\",\"pages\":\"\"},\"PeriodicalIF\":15.8000,\"publicationDate\":\"2025-02-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Magnesium and Alloys\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jma.2025.02.007\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"METALLURGY & METALLURGICAL ENGINEERING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Magnesium and Alloys","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1016/j.jma.2025.02.007","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"METALLURGY & METALLURGICAL ENGINEERING","Score":null,"Total":0}
The threat of hemorrhage from pelvic fractures: Clinicians seeking new solutions based on biomedical Mg implant
Biodegradable magnesium (Mg) materials offer significant advantages in trauma care due to their degradable nature and superior mechanical properties. This study reports the first successful use of degradable Mg clips in damage control surgery for pelvic fractures, addressing challenges associated with severe hemorrhage and high mortality rates (30–70 %). A 57-year-old male patient with pelvic fractures and traumatic shock underwent open reduction and internal fixation with Mg clips. At a six-month follow-up, imaging confirmed fracture healing, clip degradation, and no signs of rebleeding or infection, highlighting their effectiveness in precise hemorrhage control. Unlike traditional titanium clips, Mg clips degrade over time, eliminating the need for removal and reducing infection risks. This innovative approach combines Mg clips with conventional gauze packing, offering a more effective and safer alternative for managing pelvic trauma. Future large-scale clinical trials are necessary to validate these findings and establish Mg clips as a global standard for pelvic fracture treatment. Their portability and functionality hold promise for advancing emergency trauma care.
期刊介绍:
The Journal of Magnesium and Alloys serves as a global platform for both theoretical and experimental studies in magnesium science and engineering. It welcomes submissions investigating various scientific and engineering factors impacting the metallurgy, processing, microstructure, properties, and applications of magnesium and alloys. The journal covers all aspects of magnesium and alloy research, including raw materials, alloy casting, extrusion and deformation, corrosion and surface treatment, joining and machining, simulation and modeling, microstructure evolution and mechanical properties, new alloy development, magnesium-based composites, bio-materials and energy materials, applications, and recycling.