保护性sars - cov -2特异性T细胞进驻

IF 27.7 1区医学 Q1 IMMUNOLOGY

Nature Immunology Pub Date : 2025-02-28 DOI:10.1038/s41590-025-02095-w

Paul Moss

引用次数: 0

摘要

粘膜内的病毒特异性T细胞介导局部防御并建立组织驻留记忆。与病毒清除及其有效诱导相关的强大和功能性粘膜sars - cov -2特异性反应是疫苗方案的重要目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Protective SARS-CoV-2-specific T cells take up residence

查看原文本刊更多论文

Protective SARS-CoV-2-specific T cells take up residence

Virus-specific T cells within the mucosa mediate local defense and establish tissue-resident memory. Strong and functional mucosal SARS-CoV-2-specific responses associate with viral clearance and their effective induction is an important aspiration for vaccine regimens.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nature Immunology 医学-免疫学

CiteScore

40.00

自引率

2.30%

发文量

248

审稿时长

4-8 weeks

期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.