通过虚拟患者研究,分散贴片放置对肺静脉隔离射频消融耗散功率的影响。

IF 3.9 2区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Minha Anees, Zoraida Moreno Weidmann, David Viladés Medel, Jose M Guerra, Luca Gerardo-Giorda, Argyrios Petras
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引用次数: 0

摘要

射频消融术(RFA)是一种通过中断心脏异常电信号治疗心律失常的微创技术。它通过导管尖端输送交流电,交流电流经心脏肌肉组织和血液,到达患者皮肤上的分散贴片。本研究旨在验证分散贴片的放置影响RFA疗效和安全性的假设。通过优化贴片位置,可以使手术更有效,对患者的风险更小。基于患者成像数据,开发了一个3D计算机模型,以检查分散贴片(DP)定位对RFA期间心脏组织和躯干内电场分布的影响。我们使用ct分割躯干模型进行了80次计算机模拟,在使用标准(25 W)和高(90 W)功率设置时探索了各种DP和电极配置。对于每种配置,我们评估了DP在向电极附近的心脏组织输送能量方面的有效性。主要发现表明,DP的疗效显著影响电流输送到心脏组织。值得注意的是,在消融过程中使用前路贴片比后路贴片更有效地治疗左心房后部。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Impact of the dispersive patch placement on dissipated power in radiofrequency ablation for pulmonary vein isolation via a virtual patient study.

Impact of the dispersive patch placement on dissipated power in radiofrequency ablation for pulmonary vein isolation via a virtual patient study.

Impact of the dispersive patch placement on dissipated power in radiofrequency ablation for pulmonary vein isolation via a virtual patient study.

Impact of the dispersive patch placement on dissipated power in radiofrequency ablation for pulmonary vein isolation via a virtual patient study.

Radiofrequency ablation (RFA) is a minimally invasive technique for treating arrhythmias by interrupting abnormal electrical signals in the heart. Through a catheter tip, it delivers an alternating current that flows through the heart muscle tissue and the blood to a dispersive patch on the patient's skin. This study aims to test the hypothesis that the placement of the dispersive patch affects the efficacy and safety of RFA. By optimizing the patch position, the procedure could be made more effective and less risky for patients. A 3D in-silico model, based on patient imaging data, was developed to examine the effects of dispersive patch (DP) positioning on electric field distribution within cardiac tissue and the torso during RFA. We conducted 80 computer simulations using a CT-segmented torso model, exploring various DP and electrode configurations while applying standard (25 W) and high (90 W) power settings. For each configuration, we assessed the effectiveness of the DP in delivering power to cardiac tissue near the electrode. The main finding indicates that DP efficacy is significantly influenced by the current delivered to cardiac tissue. Notably, using an anterior patch during ablation proved more effective for the posterior left atrium compared to a posterior patch.

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来源期刊
Scientific Reports
Scientific Reports Natural Science Disciplines-
CiteScore
7.50
自引率
4.30%
发文量
19567
审稿时长
3.9 months
期刊介绍: We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections. Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021). •Engineering Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live. •Physical sciences Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics. •Earth and environmental sciences Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems. •Biological sciences Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. •Health sciences The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
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