注射产品的先进制造、建模和分析工具。

IF 3.5 3区医学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Pharmaceutical Research Pub Date : 2025-03-01 Epub Date: 2025-02-26 DOI:10.1007/s11095-025-03815-5

Howard Stamato, Maxwell Korang-Yeboah, Jyothi Rangineni, Xiaoming Xu, Robin Bogner

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引用次数: 0

摘要

尽管在药物的有效性和可得性方面取得了很大进展，但仍有更多的工作要做，以确保更多地获得和继续推进疾病治疗。根据最近的经验，可开发的治疗类型以及生产、表征、收集相关数据和向患者提供药物的技术的最新进展都在加快。国家制药技术和教育研究所召集了来自学术界、工业界和卫生当局的代表来评估进展。本文给出了注射药品先进制造的最新趋势，并提供了一些见解，制药商可以根据这些技术进步实施有价值的改进。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advanced Manufacturing, Modeling And Analytical Tools In Injectable Products.

Although great progress has been made in the effectiveness and availability of medicines, there is still more work to do assuring greater access and continuing to advance disease treatments. Recent advances in both the types of treatments that can be developed and the technology to produce, characterize, collect relevant data from, and deliver medicines to patients have accelerated in recent experience. The National Institute for Pharmaceutical Technology and Education assembled representatives from academia, industry, and health authorities to assess progress. This article gives a perspective on recent trends in advanced manufacturing of injectable pharmaceutical products and provides some insight from which pharmaceutical manufacturers may implement valuable improvements based on these technological advances.

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来源期刊

Pharmaceutical Research 医学-化学综合

CiteScore

6.60

自引率

5.40%

发文量

276

审稿时长

3.4 months

期刊介绍： Pharmaceutical Research, an official journal of the American Association of Pharmaceutical Scientists, is committed to publishing novel research that is mechanism-based, hypothesis-driven and addresses significant issues in drug discovery, development and regulation. Current areas of interest include, but are not limited to: -(pre)formulation engineering and processing- computational biopharmaceutics- drug delivery and targeting- molecular biopharmaceutics and drug disposition (including cellular and molecular pharmacology)- pharmacokinetics, pharmacodynamics and pharmacogenetics. Research may involve nonclinical and clinical studies, and utilize both in vitro and in vivo approaches. Studies on small drug molecules, pharmaceutical solid materials (including biomaterials, polymers and nanoparticles) biotechnology products (including genes, peptides, proteins and vaccines), and genetically engineered cells are welcome.