黄病毒与宿主相互作用和免疫反应的文献计量学分析:研究热点和趋势

IF 3 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Yuxin Xiong, Wenxin Fan, Ying Wu
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引用次数: 0

摘要

黄病毒是由受感染的蚊子和蜱虫传播的人畜共患病原体,对全球健康构成持续威胁。这些感染导致各种各样的疾病,大致分为两种表型:全身性出血性疾病,如登革热和黄热病,以及神经系统并发症,如西尼罗河病毒和寨卡病毒感染。黄病毒与人宿主细胞的相互作用对病毒的生命周期和宿主免疫的激活至关重要。研究黄病毒与宿主相互作用的分子机制对于了解病毒发病机制、控制流行病、优化治疗策略和加强公共卫生安全至关重要。黄病毒利用各种策略来逃避宿主免疫系统,了解这些机制对于开发抗病毒治疗方法至关重要。本研究采用文献计量学方法,利用CiteSpace和VOSviewer软件,分析有关黄病毒与宿主相互作用和相关免疫反应的文献。通过对发展趋势和关键研究领域的分析,为该领域的未来研究提供了见解和指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bibliometric analysis of flavivirus-host interactions and immune responses: Research hotspots and trends
Flaviviruses are zoonotic pathogens transmitted by infected mosquitoes and ticks, posing a persistent threat to global health. These infections lead to a diverse spectrum of diseases, broadly classified into two phenotypes: systemic hemorrhagic conditions, such as dengue and yellow fever, and neurological complications, exemplified by West Nile virus (WNV) and Zika virus (ZIKV) infections. The interactions between flaviviruses and human host cells are pivotal to the viral lifecycle and the activation of host immunity. Investigating the molecular mechanisms of flavivirus-host interactions is essential for understanding viral pathogenesis, managing epidemics, optimizing therapeutic strategies, and enhancing public health security. Flaviviruses utilize various strategies to evade the host immune system, and understanding these mechanisms is critical for the development of antiviral therapeutics. This study employs bibliometric methods, leveraging CiteSpace and VOSviewer software, to analyze literature on flavivirus-host interactions and the associated immune responses. By examining developmental trends and pivotal research areas, this analysis provides insights and guidance for future studies in this field.
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来源期刊
Biosafety and Health
Biosafety and Health Medicine-Infectious Diseases
CiteScore
7.60
自引率
0.00%
发文量
116
审稿时长
66 days
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