{"title":"用于癌症免疫治疗的光子触发焦亡和铁亡双功能纳米平台","authors":"Quansheng Cheng, Qingcheng Wang, Songnan Qu","doi":"10.1038/s41377-025-01757-6","DOIUrl":null,"url":null,"abstract":"<p>A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting, pH response, near-infrared fluorescence imaging, and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immunotherapy.</p>","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"24 1","pages":""},"PeriodicalIF":20.6000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy\",\"authors\":\"Quansheng Cheng, Qingcheng Wang, Songnan Qu\",\"doi\":\"10.1038/s41377-025-01757-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting, pH response, near-infrared fluorescence imaging, and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immunotherapy.</p>\",\"PeriodicalId\":18069,\"journal\":{\"name\":\"Light-Science & Applications\",\"volume\":\"24 1\",\"pages\":\"\"},\"PeriodicalIF\":20.6000,\"publicationDate\":\"2025-02-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Light-Science & Applications\",\"FirstCategoryId\":\"1089\",\"ListUrlMain\":\"https://doi.org/10.1038/s41377-025-01757-6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"OPTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Light-Science & Applications","FirstCategoryId":"1089","ListUrlMain":"https://doi.org/10.1038/s41377-025-01757-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPTICS","Score":null,"Total":0}
Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy
A dual-functional nanoplatform is demonstrated that is found to have the characteristics of cancer cell targeting, pH response, near-infrared fluorescence imaging, and lysosome targeting. It can simultaneously achieve pyroptosis and ferroptosis under the mediation of photons for cancer immunotherapy.