Aidan J Brady, Megan B Moynagh, Simon Devenney, Brendan Egan
{"title":"先进的鞋类技术，而不是急性摄入酮单酯，提高中长跑者的跑步经济性。","authors":"Aidan J Brady, Megan B Moynagh, Simon Devenney, Brendan Egan","doi":"10.1249/MSS.0000000000003682","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This study examined the separate and combined effects of advanced footwear technology and acute ingestion of a ketone monoester on running economy (RE), time to exhaustion, and other metabolic and cardiorespiratory parameters.</p><p><strong>Methods: </strong>In a four-condition, placebo-controlled, randomized crossover design, 18 middle- and long-distance runners (male/female = 10/8, V̇O 2peak = 59.4 ± 7.2 mL·kg -1 ·min -1 ) completed five 8-min stages of submaximal running (male = 10-14 km⋅h -1 , female = 9-13 km⋅h -1 ) on a motorized treadmill, immediately followed by a ramp test to volitional exhaustion. Participants consumed 500 mL of either a 10% carbohydrate solution (CHO) or 500 mg·kg -1 body mass of an (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester with flavored water (KME) 20 min before exercise, and an additional 300 mL of the 10% carbohydrate solution or 250 mg·kg -1 body mass of KME during exercise, while wearing either Nike Pegasus Turbo (PEG) or Nike ZoomX Vaporfly Next% 3 (VAP) running shoes. The four randomized conditions were PEG + CHO, PEG + KME, VAP + CHO, and VAP + KME.</p><p><strong>Results: </strong>RE was significantly improved during the third and the fourth submaximal running stages in VAP + CHO and VAP + KME compared with PEG + CHO and PEG + KME (all P < 0.05, ES = 0.53-0.84). RE was also improved during the fifth submaximal running stage in VAP + KME compared with PEG + CHO, and in VAP + CHO and VAP + KME compared with PEG + KME (all P < 0.05, ES = 0.56-0.66). No differences in RE were found between CHO and KME conditions. Time to exhaustion was significantly longer in VAP + CHO (381 ± 125 s) than PEG + CHO (356 ± 140 s, P = 0.023, ES = 0.18) and PEG + KME (329 ± 131 s, P < 0.001, ES = 0.40) and in VAP + KME (375 ± 125 s) than PEG + KME ( P < 0.001, ES = 0.35).</p><p><strong>Conclusions: </strong>Advanced footwear technology, but not the acute ingestion of a ketone monoester, improved the RE of trained male and female middle- and long-distance runners at submaximal running speeds.</p>","PeriodicalId":18426,"journal":{"name":"Medicine and Science in Sports and Exercise","volume":" ","pages":"1559-1569"},"PeriodicalIF":3.9000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Advanced Footwear Technology, But Not Acute Ingestion of a Ketone Monoester, Improves Running Economy in Middle- and Long-Distance Runners.\",\"authors\":\"Aidan J Brady, Megan B Moynagh, Simon Devenney, Brendan Egan\",\"doi\":\"10.1249/MSS.0000000000003682\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study examined the separate and combined effects of advanced footwear technology and acute ingestion of a ketone monoester on running economy (RE), time to exhaustion, and other metabolic and cardiorespiratory parameters.</p><p><strong>Methods: </strong>In a four-condition, placebo-controlled, randomized crossover design, 18 middle- and long-distance runners (male/female = 10/8, V̇O 2peak = 59.4 ± 7.2 mL·kg -1 ·min -1 ) completed five 8-min stages of submaximal running (male = 10-14 km⋅h -1 , female = 9-13 km⋅h -1 ) on a motorized treadmill, immediately followed by a ramp test to volitional exhaustion. Participants consumed 500 mL of either a 10% carbohydrate solution (CHO) or 500 mg·kg -1 body mass of an (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester with flavored water (KME) 20 min before exercise, and an additional 300 mL of the 10% carbohydrate solution or 250 mg·kg -1 body mass of KME during exercise, while wearing either Nike Pegasus Turbo (PEG) or Nike ZoomX Vaporfly Next% 3 (VAP) running shoes. The four randomized conditions were PEG + CHO, PEG + KME, VAP + CHO, and VAP + KME.</p><p><strong>Results: </strong>RE was significantly improved during the third and the fourth submaximal running stages in VAP + CHO and VAP + KME compared with PEG + CHO and PEG + KME (all P < 0.05, ES = 0.53-0.84). RE was also improved during the fifth submaximal running stage in VAP + KME compared with PEG + CHO, and in VAP + CHO and VAP + KME compared with PEG + KME (all P < 0.05, ES = 0.56-0.66). No differences in RE were found between CHO and KME conditions. Time to exhaustion was significantly longer in VAP + CHO (381 ± 125 s) than PEG + CHO (356 ± 140 s, P = 0.023, ES = 0.18) and PEG + KME (329 ± 131 s, P < 0.001, ES = 0.40) and in VAP + KME (375 ± 125 s) than PEG + KME ( P < 0.001, ES = 0.35).</p><p><strong>Conclusions: </strong>Advanced footwear technology, but not the acute ingestion of a ketone monoester, improved the RE of trained male and female middle- and long-distance runners at submaximal running speeds.</p>\",\"PeriodicalId\":18426,\"journal\":{\"name\":\"Medicine and Science in Sports and Exercise\",\"volume\":\" \",\"pages\":\"1559-1569\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medicine and Science in Sports and Exercise\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1249/MSS.0000000000003682\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"SPORT SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine and Science in Sports and Exercise","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1249/MSS.0000000000003682","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/25 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"SPORT SCIENCES","Score":null,"Total":0}
Advanced Footwear Technology, But Not Acute Ingestion of a Ketone Monoester, Improves Running Economy in Middle- and Long-Distance Runners.
Purpose: This study examined the separate and combined effects of advanced footwear technology and acute ingestion of a ketone monoester on running economy (RE), time to exhaustion, and other metabolic and cardiorespiratory parameters.
Methods: In a four-condition, placebo-controlled, randomized crossover design, 18 middle- and long-distance runners (male/female = 10/8, V̇O 2peak = 59.4 ± 7.2 mL·kg -1 ·min -1 ) completed five 8-min stages of submaximal running (male = 10-14 km⋅h -1 , female = 9-13 km⋅h -1 ) on a motorized treadmill, immediately followed by a ramp test to volitional exhaustion. Participants consumed 500 mL of either a 10% carbohydrate solution (CHO) or 500 mg·kg -1 body mass of an (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester with flavored water (KME) 20 min before exercise, and an additional 300 mL of the 10% carbohydrate solution or 250 mg·kg -1 body mass of KME during exercise, while wearing either Nike Pegasus Turbo (PEG) or Nike ZoomX Vaporfly Next% 3 (VAP) running shoes. The four randomized conditions were PEG + CHO, PEG + KME, VAP + CHO, and VAP + KME.
Results: RE was significantly improved during the third and the fourth submaximal running stages in VAP + CHO and VAP + KME compared with PEG + CHO and PEG + KME (all P < 0.05, ES = 0.53-0.84). RE was also improved during the fifth submaximal running stage in VAP + KME compared with PEG + CHO, and in VAP + CHO and VAP + KME compared with PEG + KME (all P < 0.05, ES = 0.56-0.66). No differences in RE were found between CHO and KME conditions. Time to exhaustion was significantly longer in VAP + CHO (381 ± 125 s) than PEG + CHO (356 ± 140 s, P = 0.023, ES = 0.18) and PEG + KME (329 ± 131 s, P < 0.001, ES = 0.40) and in VAP + KME (375 ± 125 s) than PEG + KME ( P < 0.001, ES = 0.35).
Conclusions: Advanced footwear technology, but not the acute ingestion of a ketone monoester, improved the RE of trained male and female middle- and long-distance runners at submaximal running speeds.
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Medicine & Science in Sports & Exercise® features original investigations, clinical studies, and comprehensive reviews on current topics in sports medicine and exercise science. With this leading multidisciplinary journal, exercise physiologists, physiatrists, physical therapists, team physicians, and athletic trainers get a vital exchange of information from basic and applied science, medicine, education, and allied health fields.
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