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IF 10.3 1区医学 Q1 UROLOGY & NEPHROLOGY

Journal of The American Society of Nephrology Pub Date : 2025-02-25 DOI:10.1681/ASN.0000000650

Cramer J Kallem, Alaa A Alghwiri, Jonathan Yabes, Sarah Erickson, Zhuoheng Han, Maria-Eleni Roumelioti, Jennifer L Steel, Mark Unruh, Manisha Jhamb

引用次数: 0

摘要

背景：肾衰竭患者的症状负担很重，许多患者在中心血液透析（HD）后症状会立即急性加重。很少有研究使用生态瞬间评估（EMA）来检查血液透析后以患者为中心的结果：方法：技术辅助协作护理（TĀCcare）试验的参与者连续 7 天每天在 4 个时间点完成由电话自动管理的日间失眠症状量表（DISS）。DISS 可得出 4 个症状域的分数：积极情绪、消极情绪、警觉认知和嗜睡/疲劳。通过线性混合模型分析，将疾病后的症状域和项目水平得分与非疾病日的类似时间点进行比较。混合模型还用于探讨透析后症状负担与人口统计学、社会心理学、血液透析治疗和疾病特异性特征之间的关系。所有分析均根据年龄、种族、性别和 Charlson 综合征指数进行了调整：对 156 名有 EMA 数据的 HD 患者进行了评估[平均年龄为（58±14）岁，55% 为男性，51% 为白人]。与非血液透析日相比，血液透析后患者的积极情绪[平均差（MD）= -0.22，95% CI (-0.29, -0.14)]和警觉认知[MD= -0.13，95% CI (-0.18, -0.08)]明显降低，而消极情绪[MD=0.12，95% CI (0.05, 0.19)]和嗜睡/疲劳[MD=0.51，95% CI (0.42, 0.61)]则明显升高。透析后症状加重总分的平均值为 0.70 ± 1.21，在最大量表范围内增加了 6%。与非透析日相比，透析后积极情绪和警觉认知得分的平均降幅分别相当于最大量表范围的4%和2%；消极情绪和嗜睡/疲劳得分的平均升幅分别相当于最大量表范围的2%和9%：结论：肾衰竭患者在接受血液透析治疗后，疲劳和情绪症状均有所恶化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Using Ecological Momentary Assessment to Redefine Postdialysis Fatigue in Patients with Kidney Failure.

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来源期刊

Journal of The American Society of Nephrology 医学-泌尿学与肾脏学

CiteScore

22.40

自引率

2.90%

发文量

492

审稿时长

3-8 weeks

期刊介绍： The Journal of the American Society of Nephrology (JASN) stands as the preeminent kidney journal globally, offering an exceptional synthesis of cutting-edge basic research, clinical epidemiology, meta-analysis, and relevant editorial content. Representing a comprehensive resource, JASN encompasses clinical research, editorials distilling key findings, perspectives, and timely reviews. Editorials are skillfully crafted to elucidate the essential insights of the parent article, while JASN actively encourages the submission of Letters to the Editor discussing recently published articles. The reviews featured in JASN are consistently erudite and comprehensive, providing thorough coverage of respective fields. Since its inception in July 1990, JASN has been a monthly publication. JASN publishes original research reports and editorial content across a spectrum of basic and clinical science relevant to the broad discipline of nephrology. Topics covered include renal cell biology, developmental biology of the kidney, genetics of kidney disease, cell and transport physiology, hemodynamics and vascular regulation, mechanisms of blood pressure regulation, renal immunology, kidney pathology, pathophysiology of kidney diseases, nephrolithiasis, clinical nephrology (including dialysis and transplantation), and hypertension. Furthermore, articles addressing healthcare policy and care delivery issues relevant to nephrology are warmly welcomed.