院前复苏开胸术治疗外伤性心脏骤停。

IF 15.7 1区 医学 Q1 SURGERY
Zane B Perkins, Robert Greenhalgh, Ewoud Ter Avest, Shadman Aziz, Andrew Whitehouse, Steve Read, Liz Foster, Frank Chege, Christine Henry, Richard Carden, Laura Kocierz, Gareth Davies, Tom Hurst, Robbie Lendrum, Stephen H Thomas, David J Lockey, Michael D Christian
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引用次数: 0

摘要

重要性:创伤性心脏骤停(TCA)在创伤护理中是一个关键的挑战,通常发生在受伤后,在有效的干预措施可用之前。目的:探讨院前复苏开胸术与TCA患者生存预后的关系。设计、环境和参与者:这项回顾性队列研究调查了1999年1月至2019年12月在伦敦进行院前复苏开胸治疗TCA的所有病例。数据分析时间为2022年7月至2023年7月。暴露:院前复苏开胸治疗TCA。主要结局和指标:主要结局为存活至出院。次要结局包括生存至入院和出院时的神经系统状况。结果:601例院外TCA患者院前行复苏开胸术。中位(IQR)年龄为25(20-37)岁;男性538例(89.5%),女性63例(10.5%)。529例(88.0%)为穿透性损伤。TCA发生在紧急呼叫后的中位数(IQR)为12(6-22)分钟,在高级创伤小组到达之前有491例(81.7%)骤停。心包填塞105例(17.5%),放血418例(69.6%),放血合并心包填塞72例(12.0%)。30例(5.0%)存活至出院,其中23例(76.6%)存活者神经系统预后良好。生存率因TCA的原因而有显著差异:105例心脏填塞患者中有22例(21%),418例出血患者中有8例(1.9%),72例合并或其他病理的患者中没有一例存活。没有幸存者超过15分钟的TCA心脏填塞和放血后5分钟。多变量分析显示,导致TCA的原因(校正优势比[aOR], 21.1;95% ci, 8.1-54.7;结论和相关性:TCA发生在损伤后不久,只有一个短暂的窗口期可用于有效干预。本研究发现,在一个成熟的、医生主导的城市院前系统中,复苏开胸术是可行的,并且与院外TCA患者的生存率提高有关,特别是在其他治疗选择有限的情况下,由心脏填塞引起的TCA。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prehospital Resuscitative Thoracotomy for Traumatic Cardiac Arrest.

Importance: Traumatic cardiac arrest (TCA) presents a critical challenge in trauma care, often occurring rapidly after injury before effective interventions are available.

Objective: To evaluate the association of prehospital resuscitative thoracotomy with survival outcomes for TCA.

Design, setting, and participants: This retrospective cohort study examined all cases of prehospital resuscitative thoracotomy for TCA in London from January 1999 to December 2019. Data were analyzed from July 2022 to July 2023.

Exposure: Prehospital resuscitative thoracotomy for TCA.

Main outcomes and measures: The primary outcome was survival to hospital discharge. Secondary outcomes included survival to hospital admission and neurological status at discharge.

Results: Prehospital resuscitative thoracotomy was undertaken in 601 patients with out-of-hospital TCA. The median (IQR) age was 25 (20-37) years; 538 (89.5%) were male and 63 (10.5%) female. A total of 529 patients (88.0%) had a penetrating mechanism of injury. TCA occurred at a median (IQR) of 12 (6-22) minutes after the emergency call, with 491 arrests (81.7%) before the advanced trauma team's arrival. TCA was the result of cardiac tamponade (105 patients, 17.5%), exsanguination (418 patients, 69.6%), and exsanguination combined with cardiac tamponade (72 patients, 12.0%). Thirty patients (5.0%) survived to hospital discharge, with a favorable neurological outcome observed in 23 survivors (76.6%). Survival varied significantly with the cause of TCA: 22 of 105 patients (21%) with cardiac tamponade, 8 of 418 patients (1.9%) with exsanguination, and none of the 72 patients with combined or other pathologies survived. There were no survivors beyond 15 minutes of TCA for cardiac tamponade and 5 minutes after exsanguination. Multivariable analysis revealed that the cause of TCA (adjusted odds ratio [aOR], 21.1; 95% CI, 8.1-54.7; P < .001), duration of TCA (aOR, 20.9; 95% CI, 4.4-100.6, P < .001), and absence of the need for internal cardiac massage (AOR, 0.2; 95% CI, 0.06-0.5; P = .001) were independently associated with survival.

Conclusions and relevance: TCA occurs soon after injury, with only a brief window available for effective intervention. This study found that resuscitative thoracotomy is feasible in a mature, physician-led, urban prehospital system and is associated with improved survival for patients with out-of-hospital TCA, particularly when caused by cardiac tamponade, in situations where other treatment options are limited.

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来源期刊
JAMA surgery
JAMA surgery SURGERY-
CiteScore
20.80
自引率
3.60%
发文量
400
期刊介绍: JAMA Surgery, an international peer-reviewed journal established in 1920, is the official publication of the Association of VA Surgeons, the Pacific Coast Surgical Association, and the Surgical Outcomes Club.It is a proud member of the JAMA Network, a consortium of peer-reviewed general medical and specialty publications.
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