{"title":"继发性骨病变取代与纵隔静脉血栓形成相关的非特异性椎体异常：巧合吗？","authors":"Chloé François, Vincent Leroy, Franck Demailly, Guillaume Collet, Clémence Parsy, Alexandre Fagart","doi":"10.1097/RLU.0000000000005720","DOIUrl":null,"url":null,"abstract":"<p><p>A 66-year-old woman with locally advanced lung adenocarcinoma underwent FDG-PET/CT, which revealed superior vena cava invasion and thrombosis of the brachiocephalic veins. Tracer injection on the side of thrombosis demonstrated hypermetabolism in the dorsal spine, likely due to collateral venous drainage. Following chemoradiotherapy and early discontinuation of immunotherapy for toxicity, she developed cervicobrachial neuralgia 18 months later. MRI showed marrow replacement lesions and FDG-PET/CT identified bone recurrence at D1, correlating with previously nonspecific fixation abnormalities. This case raises the question of whether vertebral venous stasis may favor metastatic grafting and highlights the potential need for contralateral FDG injection.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"e480-e482"},"PeriodicalIF":9.6000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Appearance of a Secondary Bone Lesion in Place of Nonspecific Vertebral Anomalies Related to Mediastinal Venous Thrombosis: Coincidence?\",\"authors\":\"Chloé François, Vincent Leroy, Franck Demailly, Guillaume Collet, Clémence Parsy, Alexandre Fagart\",\"doi\":\"10.1097/RLU.0000000000005720\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 66-year-old woman with locally advanced lung adenocarcinoma underwent FDG-PET/CT, which revealed superior vena cava invasion and thrombosis of the brachiocephalic veins. Tracer injection on the side of thrombosis demonstrated hypermetabolism in the dorsal spine, likely due to collateral venous drainage. Following chemoradiotherapy and early discontinuation of immunotherapy for toxicity, she developed cervicobrachial neuralgia 18 months later. MRI showed marrow replacement lesions and FDG-PET/CT identified bone recurrence at D1, correlating with previously nonspecific fixation abnormalities. This case raises the question of whether vertebral venous stasis may favor metastatic grafting and highlights the potential need for contralateral FDG injection.</p>\",\"PeriodicalId\":10692,\"journal\":{\"name\":\"Clinical Nuclear Medicine\",\"volume\":\" \",\"pages\":\"e480-e482\"},\"PeriodicalIF\":9.6000,\"publicationDate\":\"2025-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Nuclear Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/RLU.0000000000005720\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLU.0000000000005720","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/25 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
The Appearance of a Secondary Bone Lesion in Place of Nonspecific Vertebral Anomalies Related to Mediastinal Venous Thrombosis: Coincidence?
A 66-year-old woman with locally advanced lung adenocarcinoma underwent FDG-PET/CT, which revealed superior vena cava invasion and thrombosis of the brachiocephalic veins. Tracer injection on the side of thrombosis demonstrated hypermetabolism in the dorsal spine, likely due to collateral venous drainage. Following chemoradiotherapy and early discontinuation of immunotherapy for toxicity, she developed cervicobrachial neuralgia 18 months later. MRI showed marrow replacement lesions and FDG-PET/CT identified bone recurrence at D1, correlating with previously nonspecific fixation abnormalities. This case raises the question of whether vertebral venous stasis may favor metastatic grafting and highlights the potential need for contralateral FDG injection.
期刊介绍：
Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty.
Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.
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