吞噬性淋巴组织细胞病的FDG-PET/CT表现。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-02-25 DOI:10.1097/RLU.0000000000005780

Debra Ann Dawson, Duncan E K Sutherland

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引用次数: 0

摘要

一名44岁男子因发热、全血细胞减少症和新发皮疹入院。FDG-PET是根据非特异性的临床、影像学和活检结果而定的。结果包括CT上脂肪搁浅/模糊覆盖的皮下脂肪弥漫性FDG摄取。FDG摄取与肺内分散的亚固体/毛玻璃病变有关。脾肿大，整个骨髓FDG摄取增加。诊断考虑包括感染性与淋巴瘤过程，并确定可能的活检部位。对一个高度fdg的肺病变进行活检，诊断为继发于外周血t细胞淋巴瘤的噬血细胞性淋巴组织细胞增多症，没有其他说明。

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FDG-PET/CT Findings in Hemophagocytic Lymphohistiocytosis.

A 44-year-old man was admitted to the hospital with fever, pancytopenia, and a new rash. FDG-PET was ordered in light of nonspecific clinical, imaging, and biopsy findings. Findings included diffuse FDG uptake throughout the subcutaneous fat overlying fat stranding/haziness on CT. FDG uptake was associated with scattered subsolid/ground-glass lesions in the lungs. Splenomegaly and increased FDG uptake throughout the bone marrow were seen. Diagnostic considerations included infectious versus lymphomatous processes, and possible sites for biopsy were identified. Biopsy of a highly FDG-avid lung lesion led to a diagnosis of hemophagocytic lymphohistiocytosis secondary to peripheral T-cell lymphoma, not otherwise specified.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.