小肠血管球瘤的68Ga-DOTATOC PET/CT检查。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-06-01 Epub Date: 2025-02-25 DOI:10.1097/RLU.0000000000005714

Vincent Habouzit, Ornella Perotto, Nicolas Maillard, Rémi Grange, Violaine Yvorel

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引用次数: 0

摘要

一位57岁的女性在疑似肾移植感染的CT增强扫描中偶然发现了一个血管增生的小肠病变。病变的形态学特征提示神经内分泌肿瘤（NET），但血清嗜铬粒蛋白a和尿5-HIAA均为阴性。68Ga-DOTATOC PET/CT显示病灶内ssr -2高表达，提示NET。然而，病理检查显示弥漫性-平滑肌肌动蛋白阳性，符合血管球瘤。该病例强调了PET/CT在体内分子肿瘤表征中的应用，以及区分具有重叠分子靶点的不同肿瘤类型的挑战。

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68 Ga-DOTATOC PET/CT of Glomus Tumor of the Small Bowel.

A 57-year-old woman had an incidental finding of a hypervascular small bowel lesion on a contrast-enhanced CT scan performed for a suspected renal graft infection. The morphologic features of the lesion were suggestive of a neuroendocrine tumor (NET), but serum chromogranin A and urinary 5-HIAA were negative. 68 Ga-DOTATOC PET/CT showed high SSTR-2 expression in the lesion, suggesting a NET. However, pathologic examination revealed diffuse alpha-smooth muscle actin positivity, consistent with a glomus tumor. This case highlights the utility of PET/CT for in vivo molecular tumor characterization and the challenge of distinguishing between different tumor types with overlapping molecular targets.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.