{"title":"黑素瘤的早期检测:评估在国家卫生服务机构中全身摄影和连续数字皮肤镜成像的联合使用。","authors":"Tara Hodgkinson, Ciara Vereker, Ashley Spencer","doi":"10.1093/ced/llaf094","DOIUrl":null,"url":null,"abstract":"<p><p>Early detection of thin, stage 1A melanoma is crucial in improving patient outcomes, but this can be clinically challenging in patients with multiple atypical naevi. We report an observational study evaluating the effectiveness of a UK-based clinical nurse specialist-led total body photography (TBP) and sequential digital dermoscopic imaging (SDDI) programme for patients at high risk of developing melanoma. In total, 1680 patients underwent 6890 TBP and SDDI sessions, with 345 excision biopsies of clinically suspicious melanocytic lesions being performed (5% of sessions); 21 pT1a and pT1b melanomas (6% of biopsies), 20 melanoma in situ (6% of biopsies) and 150 dysplastic naevi (43% of biopsies) were identified. Median (range) Breslow thickness was 0.5 (0.2-1) mm; 95% of melanomas had a Breslow thickness of < 0.8 mm without ulceration (pT1a) and the number needed to biopsy was 8.41. Our UK experience demonstrates that a nurse-led programme of TBP with SDDI can be a clinically effective strategy for detection of early melanoma and melanoma in situ.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":"1406-1408"},"PeriodicalIF":2.8000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Early detection of melanoma: evaluating the combined use of total body photography and sequential digital dermoscopic imaging in a national health service setting.\",\"authors\":\"Tara Hodgkinson, Ciara Vereker, Ashley Spencer\",\"doi\":\"10.1093/ced/llaf094\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Early detection of thin, stage 1A melanoma is crucial in improving patient outcomes, but this can be clinically challenging in patients with multiple atypical naevi. We report an observational study evaluating the effectiveness of a UK-based clinical nurse specialist-led total body photography (TBP) and sequential digital dermoscopic imaging (SDDI) programme for patients at high risk of developing melanoma. In total, 1680 patients underwent 6890 TBP and SDDI sessions, with 345 excision biopsies of clinically suspicious melanocytic lesions being performed (5% of sessions); 21 pT1a and pT1b melanomas (6% of biopsies), 20 melanoma in situ (6% of biopsies) and 150 dysplastic naevi (43% of biopsies) were identified. Median (range) Breslow thickness was 0.5 (0.2-1) mm; 95% of melanomas had a Breslow thickness of < 0.8 mm without ulceration (pT1a) and the number needed to biopsy was 8.41. Our UK experience demonstrates that a nurse-led programme of TBP with SDDI can be a clinically effective strategy for detection of early melanoma and melanoma in situ.</p>\",\"PeriodicalId\":10324,\"journal\":{\"name\":\"Clinical and Experimental Dermatology\",\"volume\":\" \",\"pages\":\"1406-1408\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/ced/llaf094\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ced/llaf094","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Early detection of melanoma: evaluating the combined use of total body photography and sequential digital dermoscopic imaging in a national health service setting.
Early detection of thin, stage 1A melanoma is crucial in improving patient outcomes, but this can be clinically challenging in patients with multiple atypical naevi. We report an observational study evaluating the effectiveness of a UK-based clinical nurse specialist-led total body photography (TBP) and sequential digital dermoscopic imaging (SDDI) programme for patients at high risk of developing melanoma. In total, 1680 patients underwent 6890 TBP and SDDI sessions, with 345 excision biopsies of clinically suspicious melanocytic lesions being performed (5% of sessions); 21 pT1a and pT1b melanomas (6% of biopsies), 20 melanoma in situ (6% of biopsies) and 150 dysplastic naevi (43% of biopsies) were identified. Median (range) Breslow thickness was 0.5 (0.2-1) mm; 95% of melanomas had a Breslow thickness of < 0.8 mm without ulceration (pT1a) and the number needed to biopsy was 8.41. Our UK experience demonstrates that a nurse-led programme of TBP with SDDI can be a clinically effective strategy for detection of early melanoma and melanoma in situ.
期刊介绍:
Clinical and Experimental Dermatology (CED) is a unique provider of relevant and educational material for practising clinicians and dermatological researchers. We support continuing professional development (CPD) of dermatology specialists to advance the understanding, management and treatment of skin disease in order to improve patient outcomes.