膀胱根治术择期输尿管皮肤造口术:虚弱患者开放手术与机器人手术的单中心比较分析。

IF 4.5 3区 医学 Q1 UROLOGY & NEPHROLOGY
Maria Chiara Sighinolfi, Enrico Panio, Tommaso Calcagnile, Simone Assumma, Filippo Gavi, Luca Sarchi, Matti Sagalli, Filippo Turri, Alberto Romano, Alberto Del Nero, Paolo dell'Orto, Marco Sandri, Andrea Gregori, Franco Palmisano, Bernardo Rocco
{"title":"膀胱根治术择期输尿管皮肤造口术:虚弱患者开放手术与机器人手术的单中心比较分析。","authors":"Maria Chiara Sighinolfi, Enrico Panio, Tommaso Calcagnile, Simone Assumma, Filippo Gavi, Luca Sarchi, Matti Sagalli, Filippo Turri, Alberto Romano, Alberto Del Nero, Paolo dell'Orto, Marco Sandri, Andrea Gregori, Franco Palmisano, Bernardo Rocco","doi":"10.1590/S1677-5538.IBJU.2024.0556","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Radical cystectomy (RC) is a surgical procedure associated with high rates of morbidity. The aim of the study is to provide a comparison between robotic (RARC) and open RC (ORC) in patients elected to cutaneous ureterostomy (CUS).</p><p><strong>Materials and methods: </strong>This is a retrospective single-center cohort study performed at a high-volume institution. The study involved 64 patients undergoing RC with CUS, 42 ORC and 22 RARC. The indication for RC was based on EAU guidelines and the choice of CUS was planned due to advanced oncological stage or patient's frailty. Patient allocation to the robotic or open approach for RC was casual, determined by surgeon preference and/or the availability of a robotic operating room. The Adverse events were systematically graded utilizing the Clavien-Dindo classification system.</p><p><strong>Results: </strong>Complications of Clavien Dindo ≥ 2 occurred in 27 out of 42 (64.2%) ORC and 3/22 (13.6%) RARC (p < 0.001); complications of Clavien Dindo ≥ 3 occurred in 10/42 (23.8%) ORC and only 1/22 (4.5%) RARC, respectively (p = 0.08). Multivariable analysis revealed that robotic surgery was the only variable inversely associated with Clavien Dindo ≤ 2 complications.</p><p><strong>Conclusions: </strong>In conclusion, RARC appears to be associated with lower morbidity and reduced incidence of complications, elements that make it particularly suitable for frail patients with an elective indication for CUS.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"51 3","pages":""},"PeriodicalIF":4.5000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052034/pdf/","citationCount":"0","resultStr":"{\"title\":\"Radical Cystectomy with Elective Indication to Cutaneous Ureterostomy: Single-Center Comparative Analysis Between Open and Robotic Surgery in Frail Patients.\",\"authors\":\"Maria Chiara Sighinolfi, Enrico Panio, Tommaso Calcagnile, Simone Assumma, Filippo Gavi, Luca Sarchi, Matti Sagalli, Filippo Turri, Alberto Romano, Alberto Del Nero, Paolo dell'Orto, Marco Sandri, Andrea Gregori, Franco Palmisano, Bernardo Rocco\",\"doi\":\"10.1590/S1677-5538.IBJU.2024.0556\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Radical cystectomy (RC) is a surgical procedure associated with high rates of morbidity. The aim of the study is to provide a comparison between robotic (RARC) and open RC (ORC) in patients elected to cutaneous ureterostomy (CUS).</p><p><strong>Materials and methods: </strong>This is a retrospective single-center cohort study performed at a high-volume institution. The study involved 64 patients undergoing RC with CUS, 42 ORC and 22 RARC. The indication for RC was based on EAU guidelines and the choice of CUS was planned due to advanced oncological stage or patient's frailty. Patient allocation to the robotic or open approach for RC was casual, determined by surgeon preference and/or the availability of a robotic operating room. The Adverse events were systematically graded utilizing the Clavien-Dindo classification system.</p><p><strong>Results: </strong>Complications of Clavien Dindo ≥ 2 occurred in 27 out of 42 (64.2%) ORC and 3/22 (13.6%) RARC (p < 0.001); complications of Clavien Dindo ≥ 3 occurred in 10/42 (23.8%) ORC and only 1/22 (4.5%) RARC, respectively (p = 0.08). Multivariable analysis revealed that robotic surgery was the only variable inversely associated with Clavien Dindo ≤ 2 complications.</p><p><strong>Conclusions: </strong>In conclusion, RARC appears to be associated with lower morbidity and reduced incidence of complications, elements that make it particularly suitable for frail patients with an elective indication for CUS.</p>\",\"PeriodicalId\":49283,\"journal\":{\"name\":\"International Braz J Urol\",\"volume\":\"51 3\",\"pages\":\"\"},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052034/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Braz J Urol\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1590/S1677-5538.IBJU.2024.0556\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Braz J Urol","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1590/S1677-5538.IBJU.2024.0556","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

目的:根治性膀胱切除术(RC)是一种发病率较高的外科手术。本研究旨在对选择皮下输尿管造口术(CUS)的患者进行机器人膀胱切除术(RARC)和开放式膀胱切除术(ORC)的比较:这是一项回顾性单中心队列研究,在一家大医院进行。研究涉及 64 例接受 CUS RC 的患者,其中 42 例 ORC,22 例 RARC。RC的适应症基于EAU指南,选择CUS的原因是肿瘤晚期或患者体质虚弱。根据外科医生的偏好和/或机器人手术室的可用性,患者被随机分配到机器人或开放式RC方法。不良事件采用Clavien-Dindo分类系统进行系统分级:42 例 ORC 中有 27 例(64.2%)和 3/22 例 RARC 中有 3 例(13.6%)出现了 Clavien Dindo≥2 的并发症(p < 0.001);10/42 例 ORC 中有 10 例(23.8%)出现了 Clavien Dindo≥3 的并发症,而只有 1/22 例 RARC 中出现了 Clavien Dindo≥3 的并发症(p = 0.08)。多变量分析显示,机器人手术是唯一与克拉维恩-丁多≤2并发症成反比的变量:总之,RARC似乎与较低的发病率和较少的并发症发生率有关,这些因素使其特别适合有CUS择期指征的体弱患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radical Cystectomy with Elective Indication to Cutaneous Ureterostomy: Single-Center Comparative Analysis Between Open and Robotic Surgery in Frail Patients.

Objectives: Radical cystectomy (RC) is a surgical procedure associated with high rates of morbidity. The aim of the study is to provide a comparison between robotic (RARC) and open RC (ORC) in patients elected to cutaneous ureterostomy (CUS).

Materials and methods: This is a retrospective single-center cohort study performed at a high-volume institution. The study involved 64 patients undergoing RC with CUS, 42 ORC and 22 RARC. The indication for RC was based on EAU guidelines and the choice of CUS was planned due to advanced oncological stage or patient's frailty. Patient allocation to the robotic or open approach for RC was casual, determined by surgeon preference and/or the availability of a robotic operating room. The Adverse events were systematically graded utilizing the Clavien-Dindo classification system.

Results: Complications of Clavien Dindo ≥ 2 occurred in 27 out of 42 (64.2%) ORC and 3/22 (13.6%) RARC (p < 0.001); complications of Clavien Dindo ≥ 3 occurred in 10/42 (23.8%) ORC and only 1/22 (4.5%) RARC, respectively (p = 0.08). Multivariable analysis revealed that robotic surgery was the only variable inversely associated with Clavien Dindo ≤ 2 complications.

Conclusions: In conclusion, RARC appears to be associated with lower morbidity and reduced incidence of complications, elements that make it particularly suitable for frail patients with an elective indication for CUS.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
International Braz J Urol
International Braz J Urol UROLOGY & NEPHROLOGY-
CiteScore
4.60
自引率
21.60%
发文量
246
审稿时长
6-12 weeks
期刊介绍: Information not localized
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信