{"title":"生物传感用sers活性微/纳米机器。","authors":"Chenbing Li, Wenqing Zhang, Kai Zheng, Jianhe Guo","doi":"10.3390/bios15020115","DOIUrl":null,"url":null,"abstract":"<p><p>Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful noninvasive analytical technique with widespread applications in biochemical analysis and biomedical diagnostics. The need for highly sensitive, reproducible, and efficient detection of biomolecules in complex biological environments has driven significant advancements in SERS-based biosensing platforms. In this context, micro/nanomachines (MNMs) have garnered attention as versatile SERS-active substrates due to their unique structural and motional characteristics at the micro- and nanoscale. This review explores the advantages of integrating MNMs with SERS for biosensing, discussing recent technological advances, various propulsion strategies, and their potential in a range of analytical applications.</p>","PeriodicalId":48608,"journal":{"name":"Biosensors-Basel","volume":"15 2","pages":""},"PeriodicalIF":4.9000,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853185/pdf/","citationCount":"0","resultStr":"{\"title\":\"SERS-Active Micro/Nanomachines for Biosensing.\",\"authors\":\"Chenbing Li, Wenqing Zhang, Kai Zheng, Jianhe Guo\",\"doi\":\"10.3390/bios15020115\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful noninvasive analytical technique with widespread applications in biochemical analysis and biomedical diagnostics. The need for highly sensitive, reproducible, and efficient detection of biomolecules in complex biological environments has driven significant advancements in SERS-based biosensing platforms. In this context, micro/nanomachines (MNMs) have garnered attention as versatile SERS-active substrates due to their unique structural and motional characteristics at the micro- and nanoscale. This review explores the advantages of integrating MNMs with SERS for biosensing, discussing recent technological advances, various propulsion strategies, and their potential in a range of analytical applications.</p>\",\"PeriodicalId\":48608,\"journal\":{\"name\":\"Biosensors-Basel\",\"volume\":\"15 2\",\"pages\":\"\"},\"PeriodicalIF\":4.9000,\"publicationDate\":\"2025-02-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11853185/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biosensors-Basel\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.3390/bios15020115\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biosensors-Basel","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/bios15020115","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful noninvasive analytical technique with widespread applications in biochemical analysis and biomedical diagnostics. The need for highly sensitive, reproducible, and efficient detection of biomolecules in complex biological environments has driven significant advancements in SERS-based biosensing platforms. In this context, micro/nanomachines (MNMs) have garnered attention as versatile SERS-active substrates due to their unique structural and motional characteristics at the micro- and nanoscale. This review explores the advantages of integrating MNMs with SERS for biosensing, discussing recent technological advances, various propulsion strategies, and their potential in a range of analytical applications.
Biosensors-BaselBiochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
6.60
自引率
14.80%
发文量
983
审稿时长
11 weeks
期刊介绍:
Biosensors (ISSN 2079-6374) provides an advanced forum for studies related to the science and technology of biosensors and biosensing. It publishes original research papers, comprehensive reviews and communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Electronic files and software regarding the full details of the calculation or experimental procedure, if unable to be published in a normal way, can be deposited as supplementary electronic material.