Johannes Kögel, Peta S Cook, Nik Brown, Amy Clare, Megan H Glick, Kristofer Hansson, Markus Idvall, Susanne Lundin, Mike Michael, Sofie Á Rogvi, Lesley A Sharp
{"title":"工程器官、希望与杂交:对异种器官移植社会潜力的思考。","authors":"Johannes Kögel, Peta S Cook, Nik Brown, Amy Clare, Megan H Glick, Kristofer Hansson, Markus Idvall, Susanne Lundin, Mike Michael, Sofie Á Rogvi, Lesley A Sharp","doi":"10.1136/medhum-2024-013061","DOIUrl":null,"url":null,"abstract":"<p><p>The development of replacing human organs with those from genetically modified pigs holds immense potential for alleviating the shortage of organs necessary for patients in need of transplants. This medical advancement is also accompanied by significant social changes, including the emergence of a bioeconomy, new modes of biotechnology governance, altered human-animal relations and increased public engagement. Some aspects, such as the impact on the transplant allocation system, effects on clinical practice and healthcare provision, global trajectories and most importantly the consequences for patients and their families remain unpredictable. Given that xenotransplantation occurs within a societal context and its success or failure will not be confined to technical feasibility alone, it is essential to engage a social sciences perspective to highlight the social implications and emphasise the importance of social research in accompanying future developments.</p>","PeriodicalId":46435,"journal":{"name":"Medical Humanities","volume":"51 1","pages":"180-184"},"PeriodicalIF":1.2000,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877069/pdf/","citationCount":"0","resultStr":"{\"title\":\"Engineering organs, hopes and hybridity: considerations on the social potentialities of xenotransplantation.\",\"authors\":\"Johannes Kögel, Peta S Cook, Nik Brown, Amy Clare, Megan H Glick, Kristofer Hansson, Markus Idvall, Susanne Lundin, Mike Michael, Sofie Á Rogvi, Lesley A Sharp\",\"doi\":\"10.1136/medhum-2024-013061\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The development of replacing human organs with those from genetically modified pigs holds immense potential for alleviating the shortage of organs necessary for patients in need of transplants. This medical advancement is also accompanied by significant social changes, including the emergence of a bioeconomy, new modes of biotechnology governance, altered human-animal relations and increased public engagement. Some aspects, such as the impact on the transplant allocation system, effects on clinical practice and healthcare provision, global trajectories and most importantly the consequences for patients and their families remain unpredictable. Given that xenotransplantation occurs within a societal context and its success or failure will not be confined to technical feasibility alone, it is essential to engage a social sciences perspective to highlight the social implications and emphasise the importance of social research in accompanying future developments.</p>\",\"PeriodicalId\":46435,\"journal\":{\"name\":\"Medical Humanities\",\"volume\":\"51 1\",\"pages\":\"180-184\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2025-02-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11877069/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Humanities\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1136/medhum-2024-013061\",\"RegionNum\":3,\"RegionCategory\":\"社会学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"0\",\"JCRName\":\"HUMANITIES, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Humanities","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1136/medhum-2024-013061","RegionNum":3,"RegionCategory":"社会学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"0","JCRName":"HUMANITIES, MULTIDISCIPLINARY","Score":null,"Total":0}
Engineering organs, hopes and hybridity: considerations on the social potentialities of xenotransplantation.
The development of replacing human organs with those from genetically modified pigs holds immense potential for alleviating the shortage of organs necessary for patients in need of transplants. This medical advancement is also accompanied by significant social changes, including the emergence of a bioeconomy, new modes of biotechnology governance, altered human-animal relations and increased public engagement. Some aspects, such as the impact on the transplant allocation system, effects on clinical practice and healthcare provision, global trajectories and most importantly the consequences for patients and their families remain unpredictable. Given that xenotransplantation occurs within a societal context and its success or failure will not be confined to technical feasibility alone, it is essential to engage a social sciences perspective to highlight the social implications and emphasise the importance of social research in accompanying future developments.
期刊介绍:
Occupational and Environmental Medicine (OEM) is an international peer reviewed journal concerned with areas of current importance in occupational medicine and environmental health issues throughout the world. Original contributions include epidemiological, physiological and psychological studies of occupational and environmental health hazards as well as toxicological studies of materials posing human health risks. A CPD/CME series aims to help visitors in continuing their professional development. A World at Work series describes workplace hazards and protetctive measures in different workplaces worldwide. A correspondence section provides a forum for debate and notification of preliminary findings.