IF 3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Gianluca Galieri, Vittorio Orlando, Edoardo Mazzucchi, Fabrizio Pignotti, Davide Cusumano, Paola Bazzu, Sofia Mantini, Roberto Altieri, Manlio Barbarisi, Alessandro Olivi, Giovanni Sabatino, Giuseppe La Rocca
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引用次数: 0

摘要

背景/目的:腰椎间盘突出症(LDH)会导致下背部和腿部放射性疼痛,严重影响患者的生活质量。当保守治疗无效时,手术干预(如椎间盘切除术)可有效缓解症状;然而,焦虑、抑郁和不适应应对策略等心理因素可能会对手术效果产生负面影响。本研究旨在评估术前心理评估在预测术后恢复中的作用,并确定手术成功的关键心理和功能预测因素。方法:在 2020 年 12 月至 2023 年 12 月期间,对 888 名在 Mater Olbia 医院接受 LDH 显微椎间盘切除术的患者进行了前瞻性研究。术前评估包括视觉模拟量表、症状清单90-R、Oswestry残疾指数和短表36。采用逻辑回归模型和 ROC 曲线分析来确定重要的预后因素并评估模型的准确性。结果:术前疼痛程度和情绪健康是影响术后 Oswestry 失能指数改善的最主要决定因素。预测模型在识别可能从手术中获益的患者方面表现出很高的特异性(90.2%)。69%的患者在临床上获得了明显改善,这凸显了心理和功能评估的重要性。结论:术前心理评估对预测腰椎间盘突出症手术效果至关重要。术前应对心理因素可促进康复、支持个性化治疗计划并改善患者教育。这些研究结果主张采用综合护理模式,同时考虑生理和心理健康,优化手术效果和患者满意度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Psychopathological Influences on Surgical and Clinical Outcomes in Lumbar Disk Herniation: Prediction Models and Literature Analysis.

Background/Objectives: Lumbar disk herniation (LDH) significantly affects quality of life due to lower back and radiating leg pain. Surgical intervention, such as discectomy, is effective for symptom relief when conservative measures fail; however, psychological factors like anxiety, depression, and maladaptive coping strategies may negatively impact surgical outcomes. This study aims to assess the role of preoperative psychological evaluations in predicting postoperative recovery and to identify key psychological and functional predictors of surgical success. Methods: A prospective study was conducted on 888 patients undergoing microdiscectomy for LDH at Mater Olbia Hospital between December 2020 and December 2023. Preoperative evaluations included the Visual Analog Scale, Symptom Checklist 90-R, Oswestry Disability Index, and Short Form 36. Logistic regression models and ROC curve analysis were used to identify significant predictors of outcomes and evaluate model accuracy. Results: Preoperative pain levels and emotional well-being emerged as the strongest determinants of postoperative improvement in the Oswestry Disability Index. The predictive model demonstrated high specificity (90.2%) in identifying patients likely to benefit from surgery. Clinically significant improvements were achieved by 69% of patients, highlighting the importance of psychological and functional assessments. Conclusions: Preoperative psychological assessment is critical in predicting outcomes of lumbar disk herniation surgery. Addressing psychological factors preoperatively enhances recovery, supports personalized treatment planning, and improves patient education. These findings advocate for an integrated care model that considers both physical and psychological health, optimizing surgical outcomes and patient satisfaction.

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来源期刊
Journal of Personalized Medicine
Journal of Personalized Medicine Medicine-Medicine (miscellaneous)
CiteScore
4.10
自引率
0.00%
发文量
1878
审稿时长
11 weeks
期刊介绍: Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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