无添加剂光诱导合成功能化螺旋[2.3]己烷。

IF 2.7 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-02-13 DOI:10.1039/d5ob00055f

Dan Qi , Jinrui Bai , Yue Yao , Chao Liu

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引用次数: 0

摘要

描述了合成螺[2.3]己烷的一般绿色方案，避免使用有害和有毒试剂。仅在可见光照射下，可以利用低反应性的烯烃构建螺环支架。该方法具有条件温和、功能群容忍度好、操作简单、可扩展性强等综合优点。机理研究表明，C-C键的形成几乎与光持续引发过程同时发生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Photoinduced synthesis of functionalized spiro[2.3]hexane via an additive-free approach†

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Photoinduced synthesis of functionalized spiro[2.3]hexane via an additive-free approach†

A general green protocol for the synthesis of spiro[2.3]hexane avoiding the use of harmful and toxic reagents is described. Spirocyclic scaffolds can be constructed by using alkenes of low reactivity under visible-light irradiation only. Several synthetic advantages of this method are exhibited, including mild conditions, good functional-group tolerance, operational simplicity, and scalability. Mechanistic studies indicate that C–C bond formation occurs almost simultaneously with a light-sustained initiation process.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.