用于膀胱容量实时监测的可拉伸应变传感器

IF 8.2 2区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY
Sara Marmarchinia, Xinlei Chen, Mehmet Senel*, Gokhan Gundogdu, Joshua Mauney and Michelle Khine*, 
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引用次数: 0

摘要

尿失禁(UI)是一种普遍存在的状况,对生活质量产生不利影响,推动了对持续膀胱监测的创新技术的需求。在这项研究中,我们介绍了一种褶皱金属(铂和金)应变传感器,专门用于实时膀胱容量监测。这种可拉伸传感器的设计提供了5000次循环的坚固可靠的性能,具有最小的滞后,其机械性能与膀胱组织相匹配,可以在膀胱填充和排空期间进行准确监测。实验结果表明,该传感器具有较高的灵敏度和稳定性,动态范围高达230%应变,杨氏模量为11.7-32 kPa,测量因子(GF)为2.9-4.7。通过体外膀胱幻影研究和离体猪膀胱实验验证了该传感器的有效性,该传感器连续跟踪膀胱体积变化,灵敏度为4.60 mL-1。结果表明,应变传感器是一种有希望的候选物,用于强大的、生物相容性的膀胱容量监测泌尿系统疾病患者,提供了一种替代传统方法,更舒适和生物相容性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Stretchable Strain Sensors for Real-Time Bladder Volume Monitoring

Stretchable Strain Sensors for Real-Time Bladder Volume Monitoring

Urinary incontinence (UI) is a prevalent condition that adversely affects quality of life, driving the need for innovative technologies for continuous bladder monitoring. In this study, we introduce a wrinkled metal (platinum and gold) strain sensor tailored for real-time bladder volume monitoring. This stretchable sensor is designed to provide robust and reliable performance for 5000 cycles with minimal hysteresis, and its mechanical properties match that of bladder tissue, enabling accurate monitoring during bladder filling and emptying. Our experimental results demonstrate that the sensor offers high sensitivity and stability, with a dynamic range of up to 230% strain, Young’s modulus of 11.7–32 kPa, and a gauge factor (GF) of 2.9–4.7. The sensor’s efficacy was validated through in vitro bladder phantom studies and ex vivo pig bladder experiments, where it consistently tracked bladder volume changes with a sensitivity of 4.60 mL–1. The results suggest that the strain sensor is a promising candidate for robust, biocompatible bladder volume monitoring in patients with urinary disorders, offering an alternative to traditional methods by being more comfortable and biocompatible.

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来源期刊
ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces 工程技术-材料科学:综合
CiteScore
16.00
自引率
6.30%
发文量
4978
审稿时长
1.8 months
期刊介绍: ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.
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