Sara Marmarchinia, Xinlei Chen, Mehmet Senel*, Gokhan Gundogdu, Joshua Mauney and Michelle Khine*,
{"title":"用于膀胱容量实时监测的可拉伸应变传感器","authors":"Sara Marmarchinia, Xinlei Chen, Mehmet Senel*, Gokhan Gundogdu, Joshua Mauney and Michelle Khine*, ","doi":"10.1021/acsami.4c1915610.1021/acsami.4c19156","DOIUrl":null,"url":null,"abstract":"<p >Urinary incontinence (UI) is a prevalent condition that adversely affects quality of life, driving the need for innovative technologies for continuous bladder monitoring. In this study, we introduce a wrinkled metal (platinum and gold) strain sensor tailored for real-time bladder volume monitoring. This stretchable sensor is designed to provide robust and reliable performance for 5000 cycles with minimal hysteresis, and its mechanical properties match that of bladder tissue, enabling accurate monitoring during bladder filling and emptying. Our experimental results demonstrate that the sensor offers high sensitivity and stability, with a dynamic range of up to 230% strain, Young’s modulus of 11.7–32 kPa, and a gauge factor (GF) of 2.9–4.7. The sensor’s efficacy was validated through in vitro bladder phantom studies and ex vivo pig bladder experiments, where it consistently tracked bladder volume changes with a sensitivity of 4.60 mL<sup>–1</sup>. The results suggest that the strain sensor is a promising candidate for robust, biocompatible bladder volume monitoring in patients with urinary disorders, offering an alternative to traditional methods by being more comfortable and biocompatible.</p>","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"17 8","pages":"11678–11687 11678–11687"},"PeriodicalIF":8.2000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Stretchable Strain Sensors for Real-Time Bladder Volume Monitoring\",\"authors\":\"Sara Marmarchinia, Xinlei Chen, Mehmet Senel*, Gokhan Gundogdu, Joshua Mauney and Michelle Khine*, \",\"doi\":\"10.1021/acsami.4c1915610.1021/acsami.4c19156\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Urinary incontinence (UI) is a prevalent condition that adversely affects quality of life, driving the need for innovative technologies for continuous bladder monitoring. In this study, we introduce a wrinkled metal (platinum and gold) strain sensor tailored for real-time bladder volume monitoring. This stretchable sensor is designed to provide robust and reliable performance for 5000 cycles with minimal hysteresis, and its mechanical properties match that of bladder tissue, enabling accurate monitoring during bladder filling and emptying. Our experimental results demonstrate that the sensor offers high sensitivity and stability, with a dynamic range of up to 230% strain, Young’s modulus of 11.7–32 kPa, and a gauge factor (GF) of 2.9–4.7. The sensor’s efficacy was validated through in vitro bladder phantom studies and ex vivo pig bladder experiments, where it consistently tracked bladder volume changes with a sensitivity of 4.60 mL<sup>–1</sup>. The results suggest that the strain sensor is a promising candidate for robust, biocompatible bladder volume monitoring in patients with urinary disorders, offering an alternative to traditional methods by being more comfortable and biocompatible.</p>\",\"PeriodicalId\":5,\"journal\":{\"name\":\"ACS Applied Materials & Interfaces\",\"volume\":\"17 8\",\"pages\":\"11678–11687 11678–11687\"},\"PeriodicalIF\":8.2000,\"publicationDate\":\"2025-02-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Materials & Interfaces\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acsami.4c19156\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Materials & Interfaces","FirstCategoryId":"88","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsami.4c19156","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Stretchable Strain Sensors for Real-Time Bladder Volume Monitoring
Urinary incontinence (UI) is a prevalent condition that adversely affects quality of life, driving the need for innovative technologies for continuous bladder monitoring. In this study, we introduce a wrinkled metal (platinum and gold) strain sensor tailored for real-time bladder volume monitoring. This stretchable sensor is designed to provide robust and reliable performance for 5000 cycles with minimal hysteresis, and its mechanical properties match that of bladder tissue, enabling accurate monitoring during bladder filling and emptying. Our experimental results demonstrate that the sensor offers high sensitivity and stability, with a dynamic range of up to 230% strain, Young’s modulus of 11.7–32 kPa, and a gauge factor (GF) of 2.9–4.7. The sensor’s efficacy was validated through in vitro bladder phantom studies and ex vivo pig bladder experiments, where it consistently tracked bladder volume changes with a sensitivity of 4.60 mL–1. The results suggest that the strain sensor is a promising candidate for robust, biocompatible bladder volume monitoring in patients with urinary disorders, offering an alternative to traditional methods by being more comfortable and biocompatible.
期刊介绍:
ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.