苯丙胺类兴奋剂[2g—b]

Il Farmaco; edizione scientifica Pub Date : 1988-05-01
H Amarouch, P R Loiseau, M Bonnafous, R Caujolle, M Payard, P M Loiseau, C Bories, P Gayral
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引用次数: 0

摘要

合成了含有5,6-二氢咪唑[2,1-b]噻唑、2,3,5,6-四氢咪唑[2,1-b]噻唑和2,3-二氢咪唑[2,1-b]苯并噻唑环的新化合物,并用类似于铬的杂环取代,并在体外对三种线虫进行了筛选。结果表明,与左旋咪唑相比,其驱虫性能适中;然而,有些产品表现出相当程度的活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Dihydro-5,6-imidazo[2,1-b]thiazoles, dihydro-2,3-imidazo[2,1-b]benzothiazoles, analogs of levamisole].

New compounds containing 5,6-dihydro imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro imidazo[2,1-b]thiazole and 2,3-dihydro imidazo[2,1-b]benzothiazole rings, substituted by heterocycles analogue to chromones, were synthesized and screened against three nematodes, in vitro. The results indicate moderate anthelmintic properties, compared to levamisole; nevertheless, some products exhibit a significant degree of activity.

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