Jarrod Zamparini, Sulaiman Hassan, Natasha Davies, Wilhelm Herbst, Shastra Bhoora, Robert Nyakoe, Lawrence Chauke
{"title":"在南非的一个三级产科单位坚持艾滋病毒垂直传播预防政策。","authors":"Jarrod Zamparini, Sulaiman Hassan, Natasha Davies, Wilhelm Herbst, Shastra Bhoora, Robert Nyakoe, Lawrence Chauke","doi":"10.1177/1753495X251317263","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>HIV disproportionately affects women of childbearing age in South Africa. Despite progress in antiretroviral therapy access, challenges persist in HIV vertical transmission prevention (VTP).</p><p><strong>Methods: </strong>We conducted a single-centre, retrospective observational audit of women delivering between May and August 2023 at the Charlotte Maxeke Johannesburg Academic Hospital in Johannesburg, South Africa to assess adherence to national VTP guidelines.</p><p><strong>Results: </strong>Of 563 women, 22% (125/563) were living with HIV at their first antenatal visit, increasing to 24.3% (137/563) by delivery. HIV retesting rates declined from 46% (181/394) at the second visit to 20% (30/151) by the eighth. HIV viral load testing was performed in 71.5% of women (98/137) at delivery, with 72.4% (71/98) achieving viral suppression. Birth PCR testing was not performed for 21.1% (29/137) of HIV-exposed infants.</p><p><strong>Conclusion: </strong>Significant gaps in HIV retesting, viral load monitoring, and birth PCR testing highlight ongoing challenges in VTP guideline adherence.</p>","PeriodicalId":51717,"journal":{"name":"Obstetric Medicine","volume":" ","pages":"1753495X251317263"},"PeriodicalIF":0.5000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840821/pdf/","citationCount":"0","resultStr":"{\"title\":\"Adherence to HIV vertical transmission prevention (VTP) policies in a tertiary-level obstetric unit in South Africa.\",\"authors\":\"Jarrod Zamparini, Sulaiman Hassan, Natasha Davies, Wilhelm Herbst, Shastra Bhoora, Robert Nyakoe, Lawrence Chauke\",\"doi\":\"10.1177/1753495X251317263\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>HIV disproportionately affects women of childbearing age in South Africa. Despite progress in antiretroviral therapy access, challenges persist in HIV vertical transmission prevention (VTP).</p><p><strong>Methods: </strong>We conducted a single-centre, retrospective observational audit of women delivering between May and August 2023 at the Charlotte Maxeke Johannesburg Academic Hospital in Johannesburg, South Africa to assess adherence to national VTP guidelines.</p><p><strong>Results: </strong>Of 563 women, 22% (125/563) were living with HIV at their first antenatal visit, increasing to 24.3% (137/563) by delivery. HIV retesting rates declined from 46% (181/394) at the second visit to 20% (30/151) by the eighth. HIV viral load testing was performed in 71.5% of women (98/137) at delivery, with 72.4% (71/98) achieving viral suppression. Birth PCR testing was not performed for 21.1% (29/137) of HIV-exposed infants.</p><p><strong>Conclusion: </strong>Significant gaps in HIV retesting, viral load monitoring, and birth PCR testing highlight ongoing challenges in VTP guideline adherence.</p>\",\"PeriodicalId\":51717,\"journal\":{\"name\":\"Obstetric Medicine\",\"volume\":\" \",\"pages\":\"1753495X251317263\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11840821/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obstetric Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/1753495X251317263\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obstetric Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/1753495X251317263","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Adherence to HIV vertical transmission prevention (VTP) policies in a tertiary-level obstetric unit in South Africa.
Background: HIV disproportionately affects women of childbearing age in South Africa. Despite progress in antiretroviral therapy access, challenges persist in HIV vertical transmission prevention (VTP).
Methods: We conducted a single-centre, retrospective observational audit of women delivering between May and August 2023 at the Charlotte Maxeke Johannesburg Academic Hospital in Johannesburg, South Africa to assess adherence to national VTP guidelines.
Results: Of 563 women, 22% (125/563) were living with HIV at their first antenatal visit, increasing to 24.3% (137/563) by delivery. HIV retesting rates declined from 46% (181/394) at the second visit to 20% (30/151) by the eighth. HIV viral load testing was performed in 71.5% of women (98/137) at delivery, with 72.4% (71/98) achieving viral suppression. Birth PCR testing was not performed for 21.1% (29/137) of HIV-exposed infants.
Conclusion: Significant gaps in HIV retesting, viral load monitoring, and birth PCR testing highlight ongoing challenges in VTP guideline adherence.
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