钆基纳米结构作为双重装甲材料用于微生物治疗和癌症治疗。

IF 3 4区 医学 Q2 CHEMISTRY, APPLIED
Journal of microencapsulation Pub Date : 2025-05-01 Epub Date: 2025-02-24 DOI:10.1080/02652048.2025.2469259
Nadhir N A Jafar, Junainah Abd Hamid, Farag M A Altalbawy, Pawan Sharma, Abhishek Kumar, Shirin Shomurotova, Rafid Jihad Albadr, Kamil K Atiyah Altameemi, Hawraa Mahdi Saleh, Fakhri Alajeeli, Ahmed Mohammed Ahmed, Irfan Ahmad, Imad Ibrahim Dawood
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引用次数: 0

摘要

钆(Gd)纳米颗粒由于其独特的性质在医学治疗中具有重要的前景。本文综述了Gd纳米结构在对抗微生物威胁和推进癌症治疗策略方面的合成、表征和应用。讨论了共沉淀法、微乳液法、激光烧蚀法等合成方法,并对其进行了TEM、SEM和磁性表征。本文探讨了Gd纳米结构的抗菌效果、其在联合治疗中的潜力以及有希望的抗癌机制。生物相容性,毒性和监管方面的考虑也进行了评估。强调了Gd纳米结构研究的挑战、未来前景和新兴趋势,强调了它们在医疗应用中的变革潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gadolinium (Gd)-based nanostructures as dual-armoured materials for microbial therapy and cancer theranostics.

Gadolinium (Gd) nanoparticles hold significant promise in medical theranostics due to their unique properties. This review outlines the synthesis, characterisation, and applications of Gd nanostructures in combating microbial threats and advancing cancer theragnostic strategies. Synthesis methods such as co-precipitation, microemulsion, and laser ablation are discussed, alongside TEM, SEM, and magnetic characterisation. The antimicrobial efficacy of Gd nanostructures, their potential in combination therapy, and promising anticancer mechanisms are explored. Biocompatibility, toxicity, and regulatory considerations are also evaluated. Challenges, future perspectives, and emerging trends in Gd nanostructure research are highlighted, emphasising their transformative potential in medical applications.

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来源期刊
Journal of microencapsulation
Journal of microencapsulation 工程技术-工程:化工
CiteScore
6.30
自引率
2.60%
发文量
39
审稿时长
3 months
期刊介绍: The Journal of Microencapsulation is a well-established, peer-reviewed journal dedicated to the publication of original research findings related to the preparation, properties and uses of individually encapsulated novel small particles, as well as significant improvements to tried-and-tested techniques relevant to micro and nano particles and their use in a wide variety of industrial, engineering, pharmaceutical, biotechnology and research applications. Its scope extends beyond conventional microcapsules to all other small particulate systems such as self assembling structures that involve preparative manipulation. The journal covers: Chemistry of encapsulation materials Physics of release through the capsule wall and/or desorption from carrier Techniques of preparation, content and storage Many uses to which microcapsules are put.
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