利用实时定位系统和电子医疗记录的机器学习预测院内跌倒风险

IF 9.4 1区 医学 Q1 GERIATRICS & GERONTOLOGY
Dong Won Kim, Jihoon Seo, Sujin Kwon, Chan Min Park, Changho Han, Yujeong Kim, Jaewoong Kim, Chul Sik Kim, Seok Won Park, Dukyong Yoon, Kyoung Min Kim
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引用次数: 0

摘要

医院跌倒是医疗保健中最常见和最致命的事件,对患者的健康结果和机构护理质量构成重大风险。实时定位系统(RTLS)能够持续跟踪患者的位置,为监测身体活动的变化提供了独特的机会,这是与医院摔倒风险相关的关键因素。本研究旨在利用RTLS数据来捕捉患者的动态运动,并通过机器学习方法将其与临床信息相结合,以增强院内跌倒预测。方法采用回顾性研究方法,建立临床数据模型、RTLS数据模型和联合数据模型,并进行比较。纳入韩国龙仁Severance医院2020年3月至2022年6月的22 201例患者,通过随机抽样及相关标准,选取跌倒患者118例,非跌倒患者443例,共561例患者进行详细分析。参与者的平均年龄为70.1岁,中位年龄为71.0岁(IQR: 60.0-80.0)。在参与者中,52.6% (n = 295)为男性。本研究评估住院期间首次跌倒的发生率。使用受试者工作特征下面积(AUROC)、精确召回曲线下面积(AUPRC)和Brier评分来评估受试者的表现。采用Shapley加性解释(SHAP)法和决策曲线分析(DCA)提高模型的可解释性,评价模型的临床应用价值。结果RTLS模型对医院跌倒的预测准确率显著,AUROC为0.813 (95% CI: 0.703 ~ 0.903)。临床+ RTLS模型优于仅使用一种数据的模型,AUROC为0.847 (95% CI: 0.764-0.917), AUPRC为0.667 (95% CI: 0.472-0.816), Brier评分为0.120 (95% CI: 0.083-0.162),在性能指标上存在显著差异(p < 0.0001)。DCA证实了其更大的临床益处。SHAP分析表明,与住院早期相比,经历过跌倒的患者在跌倒前的活动时间更少,运动速度更慢,尽管他们试图多活动。此外,较高的跌倒发生率与镇静剂的使用和较高的红细胞分布宽度(RDW)水平显著相关。本研究强调了利用RTLS通过机器学习方法跟踪患者身体活动的变化来预测住院跌倒的能力。这可以改善住院期间早期跌倒风险的检测,从而预防跌倒并提高患者安全。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Predicting In-Hospital Fall Risk Using Machine Learning With Real-Time Location System and Electronic Medical Records

Predicting In-Hospital Fall Risk Using Machine Learning With Real-Time Location System and Electronic Medical Records

Background

Hospital falls are the most prevalent and fatal event in healthcare, posing significant risks to patient health outcomes and institutional care quality. Real-time location system (RTLS) enables continuous tracking of patient location, providing a unique opportunity to monitor changes in physical activity, a key factor related to the risk of falls in hospitals. This study is aimed at utilizing RTLS data to capture dynamic patient movements, integrating it with clinical information through a machine learning approach to enhance in-hospital fall predictions.

Methods

This retrospective study developed and compared three models: clinical data only, RTLS data only and a combined data model. It included 22 201 patients from Yongin Severance Hospital, South Korea, from March 2020 to June 2022, with 118 fall patients and 443 nonfall patients selected through random sampling and relevant criteria for detailed analysis, totaling 561 patients. The average age of the participants was 70.1 years, with a median of 71.0 years (IQR: 60.0–80.0). Among participants, 52.6% (n = 295) were male. This study evaluated the occurrence of the first fall during hospitalization. The performance was assessed using the area under the receiver operating characteristic (AUROC), the area under the precision-recall curve (AUPRC) and the Brier score. The Shapley additive explanations (SHAP) method and decision curve analysis (DCA) were employed to enhance model explainability and assess the clinical utility of the models.

Results

The RTLS model showed significant predictive accuracy for hospital falls, with an AUROC of 0.813 (95% CI: 0.703–0.903). The clinical + RTLS model outperformed those using only one type of data, achieving an AUROC of 0.847 (95% CI: 0.764–0.917), AUPRC of 0.667 (95% CI: 0.472–0.816) and Brier score of 0.120 (95% CI: 0.083–0.162), with significant differences in performance metrics (p < 0.0001). DCA confirmed its greater clinical benefit. SHAP analysis indicated that patients who experienced falls tended to have less active time and slower movement speed just before the fall compared to the early hospitalization period, despite attempting to move more. Additionally, higher fall incidence was significantly associated with sedative use and higher red cell distribution width (RDW) levels.

Conclusion

This study underscores the capability of utilizing RTLS to predict in-hospital falls by tracking the changes of patients' physical activity through a machine learning approach. This may improve early fall risk detection during hospitalization, thereby preventing falls and enhancing patient safety.

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来源期刊
Journal of Cachexia Sarcopenia and Muscle
Journal of Cachexia Sarcopenia and Muscle MEDICINE, GENERAL & INTERNAL-
CiteScore
13.30
自引率
12.40%
发文量
234
审稿时长
16 weeks
期刊介绍: The Journal of Cachexia, Sarcopenia and Muscle is a peer-reviewed international journal dedicated to publishing materials related to cachexia and sarcopenia, as well as body composition and its physiological and pathophysiological changes across the lifespan and in response to various illnesses from all fields of life sciences. The journal aims to provide a reliable resource for professionals interested in related research or involved in the clinical care of affected patients, such as those suffering from AIDS, cancer, chronic heart failure, chronic lung disease, liver cirrhosis, chronic kidney failure, rheumatoid arthritis, or sepsis.
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