真光束直线加速器的剂量学分析及不同处理参数下光子光束的剂量学评价

IF 2.9 3区 物理与天体物理 Q2 PHYSICS, MULTIDISCIPLINARY
Roya Feroze, Hannan Younis, Mohammad Ayaz Ahmad, M. Adil Khan, Saeed Ur Rehman, Shawn Jagnandan, Antalov Jagnandan, Mavia Anjum, Noor Ul Huda Abbasi, Esam M. Al-Shaebi, Muhammad Ajaz
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引用次数: 0

摘要

真光束直线加速器是一种最先进的设备,广泛用于癌症治疗,因为它能够提供无平坦滤波器(FFF)和平坦的光子光束。尽管具有临床意义,但其剂量学特征的详细信息仍然有限。本研究利用高分辨率二极管探测器和离子室系统地评估了6 MV、6 MV FFF和15 MV光子束能量的剂量学参数。测量范围为10 × 10 cm2至40 × 40 cm2,水深分别为Dmax、5 cm、10 cm、20 cm和30 cm,源到表面距离为100 cm。分析了包括百分比深度剂量(pdd)和光束剖面在内的关键指标,以评估光束能量、场大小和深度对剂量学的影响。NORI癌症医院和Shaukat Khanum纪念医院的测量数据比较表明,各系统的性能一致且准确。这些发现为TrueBeam加速器的剂量学行为提供了有价值的见解,有助于优化治疗方案并确保改善患者的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dosimetric analysis of true beam linear accelerators and assessment of dosimetry of photon beams for various treatment parameters

The True beam linear accelerator is a state-of-the-art device widely used in cancer treatment for its ability to deliver flattening-filter-free (FFF) and flattened photon beams. Despite its clinical significance, detailed information on its dosimetric characteristics remains limited. This study systematically evaluated dosimetric parameters for photon beam energies of 6 MV, 6 MV FFF, and 15 MV using high-resolution diode detectors and ion chambers. Measurements were conducted at a source-to-surface distance of 100 cm for field sizes ranging from 10 × 10 cm2 to 40 × 40 cm2 and depths of Dmax, 5 cm, 10 cm, 20 cm, and 30 cm in water. Key metrics, including percentage depth doses (PDDs) and beam profiles, were analyzed to assess the effect of beam energy, field size, and depth on dosimetry. Comparisons of measured data from NORI Cancer Hospital and Shaukat Khanum Memorial Hospital demonstrated consistent and accurate performance across systems. These findings provide valuable insights into the dosimetric behavior of TrueBeam accelerators, contributing to the optimization of treatment protocols and ensuring improved patient outcomes.

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来源期刊
The European Physical Journal Plus
The European Physical Journal Plus PHYSICS, MULTIDISCIPLINARY-
CiteScore
5.40
自引率
8.80%
发文量
1150
审稿时长
4-8 weeks
期刊介绍: The aims of this peer-reviewed online journal are to distribute and archive all relevant material required to document, assess, validate and reconstruct in detail the body of knowledge in the physical and related sciences. The scope of EPJ Plus encompasses a broad landscape of fields and disciplines in the physical and related sciences - such as covered by the topical EPJ journals and with the explicit addition of geophysics, astrophysics, general relativity and cosmology, mathematical and quantum physics, classical and fluid mechanics, accelerator and medical physics, as well as physics techniques applied to any other topics, including energy, environment and cultural heritage.
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