新型口服头孢菌素头孢克肟的体外活性研究。

Chemioterapia : international journal of the Mediterranean Society of Chemotherapy Pub Date : 1988-12-01

R J Fass, V L Helsel

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引用次数: 0

摘要

研究了头孢克肟和7种口服抗菌剂的体外活性。头孢克肟对流感嗜血杆菌、卡他氏布兰氏菌、大肠埃希菌、克雷伯氏菌、多样柠檬酸杆菌、变形杆菌、普罗维登斯菌、嗜水气单胞菌和链球菌的MIC90S为0.015 ~ 1微克/ml。其他肠杆菌科MIC90S≥2微克/毫升;44%的菌株被抑菌量小于或等于1微克/毫升。葡萄球菌、铜绿假单胞菌和粪肠球菌对头孢克肟耐药。

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In vitro activity of cefixime, a new oral cephalosporin.

The in vitro activities of cefixime and seven comparative oral antimicrobials were studied. MIC90S of cefixime were 0.015-1 micrograms/ml for Haemophilus influenzae, Branhamella catarrhalis, Escherichia coli, Klebsiella, Citrobacter diversus, Proteus, Providencia, Aeromonas hydrophila and Streptococcus. MIC90S for other Enterobacteriaceae were greater than or equal to 2 micrograms/ml; 44% of those strains were inhibited by less than or equal 1 microgram/ml. Staphylococcus, Psuedomonas aeruginosa and Enterococcus faecalis were resistant to cefixime.

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Chemioterapia : international journal of the Mediterranean Society of Chemotherapy

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