先天性梅毒:近十年来巴西地区的流行病学概况。

IF 1.1 4区 医学 Q2 PEDIATRICS
Maria Eugênia Costa Casagrande, Anderson Soares da Silva, Altacílio Aparecido Nunes
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引用次数: 0

摘要

先天性梅毒(CS)是通过经胎盘途径传播给胎儿在妊娠的任何阶段,当孕妇或未经治疗或治疗不充分。在这项研究中,我们旨在分析巴西CS流行病学指标的趋势。这是一项横断面研究,利用了2012年1月1日至2021年12月31日巴西各地区的CS数据。计算了发病率、流行率和病死率等流行病学指标。在评估期间,巴西共记录了192 055例CS病例。在接受产前护理的孕妇中,58.5%在怀孕期间被诊断,33.9%在出生时被诊断,7.5%在出生后被诊断。在77.5%的通报中,伴侣没有得到治疗。在产前护理期间诊断的平均病例数比未报告的病例高5.6倍。东南地区每1000名活产婴儿的发病率最高,而中西部地区的发病率最低。尽管所有地区和巴西的总体发病率都有所上升,但两个评估期的平均值之间没有显著差异(p值为0.05)。但p值明显下降
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Congenital syphilis: epidemiological profile of Brazilian regions in the last decade.

Congenital syphilis (CS) is transmitted to the fetus through the transplacental route at any stage of gestation when the pregnant women are either untreated or inadequately treated. In this study, we aimed to analyze trends in epidemiological indicators of CS in Brazil. This is a cross-sectional study utilizing data on CS across Brazilian regions from 1 January 2012 to 31 December 2021. Epidemiological indicators such as incidence, prevalence, and case-fatality rates were calculated. During the evaluated period, 192 055 CS cases were recorded in Brazil. Among pregnant women who underwent prenatal care, 58.5% were diagnosed during pregnancy, 33.9% at the time of birth, and 7.5% after birth. In 77.5% of the notifications, the partners were not treated. The average number of cases diagnosed during prenatal care was 5.6 times higher than those not reported. The Southeast region presented the highest incidence rate per 1000 live births, whereas the Midwest region had the lowest incidence. Despite an increase in rates across all regions and Brazil overall, there was no significant difference (P-value > .05) between the means for the two evaluated periods. However, there was a significant decrease (P-value < .05) in the case-fatality rate in the Northeast (1.9%-1.25%) and South (2.15%-0.92%) regions, as well as throughout Brazil (from 1.77% to 1.24%). The findings indicate that the incidence rates of CS continue to rise, suggesting that the disease remains a significant public health issue in Brazil. Effective preventive measures are urgently required.

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来源期刊
Journal of Tropical Pediatrics
Journal of Tropical Pediatrics 医学-热带医学
CiteScore
4.00
自引率
0.00%
发文量
97
审稿时长
6-12 weeks
期刊介绍: The Journal of Tropical Pediatrics provides a link between theory and practice in the field. Papers report key results of clinical and community research, and considerations of programme development. More general descriptive pieces are included when they have application to work preceeding elsewhere. The journal also presents review articles, book reviews and, occasionally, short monographs and selections of important papers delivered at relevant conferences.
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