马齿苋中一种新的生物碱及其抗炎、抗氧化活性

IF 0.8 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2025-02-05 DOI:10.1007/s10600-025-04586-6

Yingdai Zhao, Yang Du, Hongzhe Zhang, Aijing Leng, Xixiang Ying

{"title":"马齿苋中一种新的生物碱及其抗炎、抗氧化活性","authors":"Yingdai Zhao, Yang Du, Hongzhe Zhang, Aijing Leng, Xixiang Ying","doi":"10.1007/s10600-025-04586-6","DOIUrl":null,"url":null,"abstract":"A new alkaloid, (S)-1-methyl-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6,7-diol (1), named oleraisoquinoline A, and 9 known compounds, iseluxine (2), oleracrylimide E (3), oleracrylimide A (4), oleracrylimide B (5), chrysoeriol (6), 2-(2-hydroxyphenyl)-5,7-dimethoxychroman-4-one (7), portulacanone C (8), portulacanone D (9), and 2,2′-dihydroxy-4′,6′-dimethoxychalcone (10), were obtained from P. oleracea, in which, compounds 6, 7 were isolated from the plant for the first time. The structure of compound 1, identified by UHPLC-ESI-Q-TOF/MS, 1D, 2D NMR, and CD, presented remarkable anti-inflammatory and antioxidant activities, as also did compound 2, while 6 presented antioxidant activities.","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":"61 1","pages":"114 - 118"},"PeriodicalIF":0.8000,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A New Alkaloid from Portulaca oleracea and Its Anti-Inflammatory and Antioxidant Activities\",\"authors\":\"Yingdai Zhao, Yang Du, Hongzhe Zhang, Aijing Leng, Xixiang Ying\",\"doi\":\"10.1007/s10600-025-04586-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A new alkaloid, (S)-1-methyl-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6,7-diol (1), named oleraisoquinoline A, and 9 known compounds, iseluxine (2), oleracrylimide E (3), oleracrylimide A (4), oleracrylimide B (5), chrysoeriol (6), 2-(2-hydroxyphenyl)-5,7-dimethoxychroman-4-one (7), portulacanone C (8), portulacanone D (9), and 2,2′-dihydroxy-4′,6′-dimethoxychalcone (10), were obtained from P. oleracea, in which, compounds 6, 7 were isolated from the plant for the first time. The structure of compound 1, identified by UHPLC-ESI-Q-TOF/MS, 1D, 2D NMR, and CD, presented remarkable anti-inflammatory and antioxidant activities, as also did compound 2, while 6 presented antioxidant activities.\",\"PeriodicalId\":514,\"journal\":{\"name\":\"Chemistry of Natural Compounds\",\"volume\":\"61 1\",\"pages\":\"114 - 118\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-02-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemistry of Natural Compounds\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s10600-025-04586-6\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry of Natural Compounds","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10600-025-04586-6","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}

引用次数: 0

摘要

新生物碱(S) 1-methyl-2-nitroso-1, 2, 3, 4-tetrahydroisoquinoline-6, 7-diol(1),名叫oleraisoquinoline,和9个已知化合物,iseluxine (2), oleracrylimide E (3), oleracrylimide (4), oleracrylimide B (5), chrysoeriol (6), 2 - 5 (2-hydroxyphenyl), 7-dimethoxychroman-4-one (7), portulacanone C (8), portulacanone D(9),和2,2‘-dihydroxy-4’,6’-dimethoxychalcone(10),得到从p . oleracea,化合物6,7第一次被孤立于植物。通过UHPLC-ESI-Q-TOF/MS、1D、2D NMR和CD鉴定，化合物1的结构具有明显的抗炎和抗氧化活性，化合物2也具有明显的抗氧化活性，化合物6具有明显的抗氧化活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A New Alkaloid from Portulaca oleracea and Its Anti-Inflammatory and Antioxidant Activities

查看原文本刊更多论文

A New Alkaloid from Portulaca oleracea and Its Anti-Inflammatory and Antioxidant Activities

A new alkaloid, (S)-1-methyl-2-nitroso-1,2,3,4-tetrahydroisoquinoline-6,7-diol (1), named oleraisoquinoline A, and 9 known compounds, iseluxine (2), oleracrylimide E (3), oleracrylimide A (4), oleracrylimide B (5), chrysoeriol (6), 2-(2-hydroxyphenyl)-5,7-dimethoxychroman-4-one (7), portulacanone C (8), portulacanone D (9), and 2,2′-dihydroxy-4′,6′-dimethoxychalcone (10), were obtained from P. oleracea, in which, compounds 6, 7 were isolated from the plant for the first time. The structure of compound 1, identified by UHPLC-ESI-Q-TOF/MS, 1D, 2D NMR, and CD, presented remarkable anti-inflammatory and antioxidant activities, as also did compound 2, while 6 presented antioxidant activities.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.