Kanagavel Yathwin, Rajiv Raj D., Vittalraj Pavitra, Sanjanika S., Balaji Singh K.
{"title":"与igg4相关的睾丸旁纤维性假瘤-一种罕见的良性睾丸恶性肿瘤:1例报告及文献复习","authors":"Kanagavel Yathwin, Rajiv Raj D., Vittalraj Pavitra, Sanjanika S., Balaji Singh K.","doi":"10.1016/j.eucr.2025.102989","DOIUrl":null,"url":null,"abstract":"<div><div>Para-testicular fibrous pseudotumors (PFP) are rare benign reactive lesions comprising of 6 % of para-testicular masses. Often misdiagnosed as malignant due to clinical and radiological overlap, they are frequently treated with aggressive surgery. We report a case of a 70-year-old male with a left inguinal swelling diagnosed post-orchidectomy as PFP. Histopathology revealed collagen-rich fibrotic tissue with lymphoplasmacytic infiltrates and IgG4-positive plasma cells. While PFP treatment requires surgical resection, testicle-sparing procedures with intraoperative frozen section assessment may prevent unnecessary orchidectomy. Further studies are needed to establish diagnostic protocols and explore the association between PFP and IgG4-related diseases.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"59 ","pages":"Article 102989"},"PeriodicalIF":0.5000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"IgG4-related para-testicular fibrous pseudotumor- A rare benign testicular mass mimicking malignancy: A case report and literature review\",\"authors\":\"Kanagavel Yathwin, Rajiv Raj D., Vittalraj Pavitra, Sanjanika S., Balaji Singh K.\",\"doi\":\"10.1016/j.eucr.2025.102989\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Para-testicular fibrous pseudotumors (PFP) are rare benign reactive lesions comprising of 6 % of para-testicular masses. Often misdiagnosed as malignant due to clinical and radiological overlap, they are frequently treated with aggressive surgery. We report a case of a 70-year-old male with a left inguinal swelling diagnosed post-orchidectomy as PFP. Histopathology revealed collagen-rich fibrotic tissue with lymphoplasmacytic infiltrates and IgG4-positive plasma cells. While PFP treatment requires surgical resection, testicle-sparing procedures with intraoperative frozen section assessment may prevent unnecessary orchidectomy. Further studies are needed to establish diagnostic protocols and explore the association between PFP and IgG4-related diseases.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"59 \",\"pages\":\"Article 102989\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-02-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025000609\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025000609","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
IgG4-related para-testicular fibrous pseudotumor- A rare benign testicular mass mimicking malignancy: A case report and literature review
Para-testicular fibrous pseudotumors (PFP) are rare benign reactive lesions comprising of 6 % of para-testicular masses. Often misdiagnosed as malignant due to clinical and radiological overlap, they are frequently treated with aggressive surgery. We report a case of a 70-year-old male with a left inguinal swelling diagnosed post-orchidectomy as PFP. Histopathology revealed collagen-rich fibrotic tissue with lymphoplasmacytic infiltrates and IgG4-positive plasma cells. While PFP treatment requires surgical resection, testicle-sparing procedures with intraoperative frozen section assessment may prevent unnecessary orchidectomy. Further studies are needed to establish diagnostic protocols and explore the association between PFP and IgG4-related diseases.