{"title":"Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections.","authors":"Moshe Beiser, Joshua K Sabari","doi":"10.1159/000542928","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia.</p><p><strong>Case: </strong>In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient's repeated presentation despite receiving outpatient treatment with nirmatrelvir-ritonavir. We describe the patient's presentation, diagnosis, and treatment - including robotic thymectomy and passive immunization with IVIG - and report the benefit to quality of life that the patient experienced.</p><p><strong>Conclusion: </strong>This case highlights the importance of quantitative testing of immunoglobulins in patients with known thymomas who present with recurrent infections of SARS-CoV-2.</p>","PeriodicalId":9625,"journal":{"name":"Case Reports in Oncology","volume":"18 1","pages":"107-112"},"PeriodicalIF":0.7000,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731910/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000542928","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景：病例：在本病例报告中，我们介绍了一名因反复感染 SARS-CoV-2 而被诊断为 Good 综合征的患者。特别值得注意的是，尽管患者接受了尼马瑞韦-利托那韦的门诊治疗，但仍反复发病。我们描述了患者的表现、诊断和治疗（包括机器人胸腺切除术和 IVIG 被动免疫），并报告了患者的生活质量受益情况：本病例强调了对已知胸腺瘤但反复感染 SARS-CoV-2 的患者进行免疫球蛋白定量检测的重要性。
Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections.
Background: Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia.
Case: In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient's repeated presentation despite receiving outpatient treatment with nirmatrelvir-ritonavir. We describe the patient's presentation, diagnosis, and treatment - including robotic thymectomy and passive immunization with IVIG - and report the benefit to quality of life that the patient experienced.
Conclusion: This case highlights the importance of quantitative testing of immunoglobulins in patients with known thymomas who present with recurrent infections of SARS-CoV-2.
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