Simone Scuderi, Amy L Tin, Jared Klug, Shaun Porwal, Leonardo Quarta, Margherita Ciabattini, Nazario Pio Tenace, Riccardo Leni, Roberta Lucianò, Armando Stabile, Giorgio Gandaglia, James A Eastham, Francesco Montorsi, Alberto Briganti, Andrew J Vickers
{"title":"根治性前列腺切除术中Gleason 4型肿瘤的绝对体积与晚期和生化复发的相关性高于Gleason分级组。","authors":"Simone Scuderi, Amy L Tin, Jared Klug, Shaun Porwal, Leonardo Quarta, Margherita Ciabattini, Nazario Pio Tenace, Riccardo Leni, Roberta Lucianò, Armando Stabile, Giorgio Gandaglia, James A Eastham, Francesco Montorsi, Alberto Briganti, Andrew J Vickers","doi":"10.1097/ju.0000000000004484","DOIUrl":null,"url":null,"abstract":"ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume is more strongly associated with advanced stage and biochemical recurrence than GG in patients with pattern 4 but not 5.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"20 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The absolute volume of Gleason Pattern 4 on radical prostatectomy is more strongly associated with advanced stage and biochemical recurrence than Gleason grade groups.\",\"authors\":\"Simone Scuderi, Amy L Tin, Jared Klug, Shaun Porwal, Leonardo Quarta, Margherita Ciabattini, Nazario Pio Tenace, Riccardo Leni, Roberta Lucianò, Armando Stabile, Giorgio Gandaglia, James A Eastham, Francesco Montorsi, Alberto Briganti, Andrew J Vickers\",\"doi\":\"10.1097/ju.0000000000004484\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume is more strongly associated with advanced stage and biochemical recurrence than GG in patients with pattern 4 but not 5.\",\"PeriodicalId\":501636,\"journal\":{\"name\":\"The Journal of Urology\",\"volume\":\"20 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Urology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/ju.0000000000004484\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ju.0000000000004484","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The absolute volume of Gleason Pattern 4 on radical prostatectomy is more strongly associated with advanced stage and biochemical recurrence than Gleason grade groups.
ISUP Grade-Group (GG) is based on the relative proportion of Gleason patterns 3 and 4. We investigated whether absolute pattern 4 volume is more strongly associated with advanced stage and biochemical recurrence than GG in patients with pattern 4 but not 5.