用GAN支持的深度学习模型诊断肺癌。

IF 1 4区 医学 Q4 ENGINEERING, BIOMEDICAL
Bio-medical materials and engineering Pub Date : 2025-07-01 Epub Date: 2025-01-31 DOI:10.1177/09592989241308775
Talip Çay
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引用次数: 0

摘要

背景:肺癌是世界范围内癌症相关死亡的主要原因,早期诊断对于提高治疗成功率和生存率至关重要。传统的诊断方法,如活检和手动CT图像解释,既耗时又容易变化,因此需要更高效、更准确的工具。深度学习的进步通过实现更快、更客观的医学图像分析,提供了有前途的解决方案。目的:本研究旨在利用先进的深度学习技术,包括专门开发的CNN模型,对肺CT良性、恶性和正常图像进行分类,以提高诊断准确率。方法:采用gan对1097张肺部CT图像进行平衡,并采用直方图均衡化和降噪等技术进行预处理。数据被分成70%的训练集和30%的测试集。模型包括VGG19、AlexNet、InceptionV3、ResNet50和定制设计的CNN。此外,集成了更快的基于r - cnn的区域建议方法,以提高检测性能。结果:自定义CNN模型达到了99%的最高准确率,超过了VGG19等其他架构的97%。更快的R-CNN集成进一步提高了灵敏度和分类精度。结论:gan支持的深度学习模型用于肺癌分类的有效性,突出了其在早期发现和诊断方面的潜在临床应用价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lung cancer diagnosis with GAN supported deep learning models.

BackgroundLung cancer is a leading cause of cancer-related deaths worldwide, making early diagnosis crucial for improving treatment success and survival rates. Traditional diagnostic methods, such as biopsy and manual CT image interpretation, are time-consuming and prone to variability, highlighting the need for more efficient and accurate tools. Advances in deep learning offer promising solutions by enabling faster and more objective medical image analysis.ObjectiveThis study aims to classify benign, malignant, and normal lung CT images using advanced deep learning techniques, including a specially developed CNN model, to improve diagnostic accuracy.MethodsA dataset of 1097 lung CT images was balanced using GANs and preprocessed with techniques like histogram equalization and noise reduction. The data was split into 70% training and 30% testing sets. Models including VGG19, AlexNet, InceptionV3, ResNet50, and a custom-designed CNN were trained. Additionally, Faster R-CNN-based region proposal methods were integrated to enhance detection performance.ResultsThe custom CNN model achieved the highest accuracy at 99%, surpassing other architectures like VGG19, which reached 97%. The Faster R-CNN integration further improved sensitivity and classification precision.ConclusionThe results demonstrate the effectiveness of GAN-supported deep learning models for lung cancer classification, highlighting their potential clinical applications for early detection and diagnosis.

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来源期刊
Bio-medical materials and engineering
Bio-medical materials and engineering 工程技术-材料科学:生物材料
CiteScore
1.80
自引率
0.00%
发文量
73
审稿时长
6 months
期刊介绍: The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.
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