{"title":"部分CO2激光术后湿性创面愈合疗效评价","authors":"Qingmei Jin, Richeng Dong, Jiahui Zhi, Huimin Yin, Meilan Nan, Zhehu Jin, Chenglong Jin","doi":"10.1111/jocd.70079","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>With the popularization of laser therapy, an increasing number of patients are undergoing fractional CO<sub>2</sub> laser therapy. It is particularly important to exercise caution and accelerate wound healing after laser surgery.</p>\n </section>\n \n <section>\n \n <h3> Aims</h3>\n \n <p>This study aimed to examine the clinical efficacy of moist wound healing after fractional CO<sub>2</sub> laser therapy.</p>\n </section>\n \n <section>\n \n <h3> Patients/Methods</h3>\n \n <p>A total of 15 individuals volunteered to undergo fractional CO<sub>2</sub> laser therapy. The facial skin was irradiated with a fractional CO<sub>2</sub> laser in the deep mode, with an energy of 15 mJ/cm<sup>2</sup> and a density of 5%. The left and right sides of the faces were considered the observation and control groups, respectively. After laser therapy, medical cold compress patches were applied on the skin in the control group once a day for approximately 10–15 min, whereas erythromycin ophthalmic ointment was applied on the skin in the observation group 6 times daily for wound care. The wound healing time, duration of erythema, and occurrence of adverse reactions were monitored in both groups.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The observation and control groups received different nursing interventions. The time to regression of erythema and swelling was significantly shorter in the observation group than in the control group. In addition, the scab formed at the wound site was thinner, and shedding was faster in the observation group than in the control group. The Clinical Erythema Assessment score of the observation group was significantly lower than that of the control group (<i>p</i> < 0.05). The wound healing time was 5.73 ± 0.70 days in the observation group and 7.73 ± 0.72 days in the control group, with the difference being statistically significant (<i>p</i> < 0.05). After 30 min and 12 h of nursing intervention, the Visual Analog Scale score of the observation group was significantly lower than that of the control group (<i>p</i> < 0.05). However, after 24 h of treatment, neither group showed significant pain. Both groups showed varying degrees of acne, pustules, and exudation, which subsided within 7 days. Furthermore, the control group had 2 cases of mild pigmentation, which resolved within 3 months. Neither group experienced adverse reactions such as skin infection, depigmentation, or scar formation.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Moist healing therapy can accelerate wound healing and reduce the duration of erythema and edema after fractional CO<sub>2</sub> laser therapy, demonstrating potential clinical application value.</p>\n </section>\n </div>","PeriodicalId":15546,"journal":{"name":"Journal of Cosmetic Dermatology","volume":"24 2","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70079","citationCount":"0","resultStr":"{\"title\":\"Evaluation of the Therapeutic Efficacy of Moist Wound Healing After Fractional CO2 Laser Surgery\",\"authors\":\"Qingmei Jin, Richeng Dong, Jiahui Zhi, Huimin Yin, Meilan Nan, Zhehu Jin, Chenglong Jin\",\"doi\":\"10.1111/jocd.70079\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>With the popularization of laser therapy, an increasing number of patients are undergoing fractional CO<sub>2</sub> laser therapy. It is particularly important to exercise caution and accelerate wound healing after laser surgery.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Aims</h3>\\n \\n <p>This study aimed to examine the clinical efficacy of moist wound healing after fractional CO<sub>2</sub> laser therapy.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Patients/Methods</h3>\\n \\n <p>A total of 15 individuals volunteered to undergo fractional CO<sub>2</sub> laser therapy. The facial skin was irradiated with a fractional CO<sub>2</sub> laser in the deep mode, with an energy of 15 mJ/cm<sup>2</sup> and a density of 5%. The left and right sides of the faces were considered the observation and control groups, respectively. After laser therapy, medical cold compress patches were applied on the skin in the control group once a day for approximately 10–15 min, whereas erythromycin ophthalmic ointment was applied on the skin in the observation group 6 times daily for wound care. The wound healing time, duration of erythema, and occurrence of adverse reactions were monitored in both groups.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The observation and control groups received different nursing interventions. The time to regression of erythema and swelling was significantly shorter in the observation group than in the control group. In addition, the scab formed at the wound site was thinner, and shedding was faster in the observation group than in the control group. The Clinical Erythema Assessment score of the observation group was significantly lower than that of the control group (<i>p</i> < 0.05). The wound healing time was 5.73 ± 0.70 days in the observation group and 7.73 ± 0.72 days in the control group, with the difference being statistically significant (<i>p</i> < 0.05). After 30 min and 12 h of nursing intervention, the Visual Analog Scale score of the observation group was significantly lower than that of the control group (<i>p</i> < 0.05). However, after 24 h of treatment, neither group showed significant pain. Both groups showed varying degrees of acne, pustules, and exudation, which subsided within 7 days. Furthermore, the control group had 2 cases of mild pigmentation, which resolved within 3 months. Neither group experienced adverse reactions such as skin infection, depigmentation, or scar formation.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Moist healing therapy can accelerate wound healing and reduce the duration of erythema and edema after fractional CO<sub>2</sub> laser therapy, demonstrating potential clinical application value.</p>\\n </section>\\n </div>\",\"PeriodicalId\":15546,\"journal\":{\"name\":\"Journal of Cosmetic Dermatology\",\"volume\":\"24 2\",\"pages\":\"\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.70079\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cosmetic Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70079\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cosmetic Dermatology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jocd.70079","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Evaluation of the Therapeutic Efficacy of Moist Wound Healing After Fractional CO2 Laser Surgery
Background
With the popularization of laser therapy, an increasing number of patients are undergoing fractional CO2 laser therapy. It is particularly important to exercise caution and accelerate wound healing after laser surgery.
Aims
This study aimed to examine the clinical efficacy of moist wound healing after fractional CO2 laser therapy.
Patients/Methods
A total of 15 individuals volunteered to undergo fractional CO2 laser therapy. The facial skin was irradiated with a fractional CO2 laser in the deep mode, with an energy of 15 mJ/cm2 and a density of 5%. The left and right sides of the faces were considered the observation and control groups, respectively. After laser therapy, medical cold compress patches were applied on the skin in the control group once a day for approximately 10–15 min, whereas erythromycin ophthalmic ointment was applied on the skin in the observation group 6 times daily for wound care. The wound healing time, duration of erythema, and occurrence of adverse reactions were monitored in both groups.
Results
The observation and control groups received different nursing interventions. The time to regression of erythema and swelling was significantly shorter in the observation group than in the control group. In addition, the scab formed at the wound site was thinner, and shedding was faster in the observation group than in the control group. The Clinical Erythema Assessment score of the observation group was significantly lower than that of the control group (p < 0.05). The wound healing time was 5.73 ± 0.70 days in the observation group and 7.73 ± 0.72 days in the control group, with the difference being statistically significant (p < 0.05). After 30 min and 12 h of nursing intervention, the Visual Analog Scale score of the observation group was significantly lower than that of the control group (p < 0.05). However, after 24 h of treatment, neither group showed significant pain. Both groups showed varying degrees of acne, pustules, and exudation, which subsided within 7 days. Furthermore, the control group had 2 cases of mild pigmentation, which resolved within 3 months. Neither group experienced adverse reactions such as skin infection, depigmentation, or scar formation.
Conclusion
Moist healing therapy can accelerate wound healing and reduce the duration of erythema and edema after fractional CO2 laser therapy, demonstrating potential clinical application value.
期刊介绍:
The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques.
The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.