Tahira Khurram, Ghalia Missous, Nicholas van Panhuys, Mohammed Yousuf Karim
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The search strategy followed the PRISMA guidelines and was conducted across PubMed, Scopus, Web of Science, and Google Scholar from inception to November 12, 2023.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>A total of 27 studies, both adult and pediatric, were included in this systematic review. Aeroallergen sensitization was assessed using skin prick testing (SPT) in 15 studies; 5 used in vitro methods, 2 employed both, 4 relied on self-reports, and 1 on aerobiological monitoring. Sensitization rates varied considerably, influenced by factors such as age, demographics, and location. Sensitization was noted to allergens shared with Western populations, and to those native to the region for example, house dust mite sensitization ranged from 15% to 78%, Salsola from 13% to 78%. Up to 65.1% of allergen-positive individuals demonstrated polysensitization. Sensitization patterns differed between indigenous populations and expatriates, with local allergens being more prevalent among natives. Sensitization rates were lower in younger children but increased with age.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Our systematic review highlights the crucial importance of providing allergen-sensitivity information that is specifically tailored to the local environment. This tailored approach can improve clinical diagnosis, enable appropriate allergen avoidance and immunotherapy strategies, and result in potential cost savings.</p>\n </section>\n </div>","PeriodicalId":10334,"journal":{"name":"Clinical and Translational Allergy","volume":"15 2","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/clt2.70033","citationCount":"0","resultStr":"{\"title\":\"Aeroallergen sensitivity patterns in Gulf countries: A systematic review\",\"authors\":\"Tahira Khurram, Ghalia Missous, Nicholas van Panhuys, Mohammed Yousuf Karim\",\"doi\":\"10.1002/clt2.70033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Successful management of allergic diseases necessitates accurate diagnosis, implementation of appropriate allergen avoidance techniques, and medical therapies. 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引用次数: 0
摘要
背景变态反应性疾病的成功管理需要准确的诊断,实施适当的过敏原避免技术和药物治疗。然而,关于海湾合作委员会(GCC)国家空气过敏原的数据是有限的。方法:我们对海湾国家中诊断为空气过敏原敏感性或进行空气过敏原敏感性测试的个体进行了系统综述,重点关注患病率和呼吸健康影响。搜索策略遵循PRISMA指南,并在PubMed, Scopus, Web of Science和b谷歌Scholar上进行,从成立到2023年11月12日。结果本系统综述共纳入了27项研究,包括成人和儿童。15项研究采用皮肤点刺试验(SPT)评估气敏原致敏性;5例采用体外法,2例两者均采用,4例采用自我报告,1例采用生物监测。受年龄、人口统计和地理位置等因素的影响,致敏率变化很大。例如,对西方人群共有的过敏原和该地区原产过敏原的致敏性,屋尘螨的致敏性从15%到78%不等,Salsola的致敏性从13%到78%不等。高达65.1%的过敏原阳性个体表现为多致敏。致敏模式在本地人和外籍人士之间有所不同,本地过敏原在本地人中更为普遍。年幼儿童的致敏率较低,但随着年龄的增长而增加。结论:我们的系统综述强调了提供适合当地环境的过敏原敏感性信息的重要性。这种量身定制的方法可以改善临床诊断,实现适当的过敏原避免和免疫治疗策略,并导致潜在的成本节约。
Aeroallergen sensitivity patterns in Gulf countries: A systematic review
Background
Successful management of allergic diseases necessitates accurate diagnosis, implementation of appropriate allergen avoidance techniques, and medical therapies. However, data availability regarding aeroallergens in the Gulf Cooperation Council (GCC) countries is limited.
Methods
We conducted a systematic review of studies conducted in Gulf countries on individuals diagnosed with or tested for aeroallergen sensitivities, focusing on prevalence and respiratory health impacts. The search strategy followed the PRISMA guidelines and was conducted across PubMed, Scopus, Web of Science, and Google Scholar from inception to November 12, 2023.
Results
A total of 27 studies, both adult and pediatric, were included in this systematic review. Aeroallergen sensitization was assessed using skin prick testing (SPT) in 15 studies; 5 used in vitro methods, 2 employed both, 4 relied on self-reports, and 1 on aerobiological monitoring. Sensitization rates varied considerably, influenced by factors such as age, demographics, and location. Sensitization was noted to allergens shared with Western populations, and to those native to the region for example, house dust mite sensitization ranged from 15% to 78%, Salsola from 13% to 78%. Up to 65.1% of allergen-positive individuals demonstrated polysensitization. Sensitization patterns differed between indigenous populations and expatriates, with local allergens being more prevalent among natives. Sensitization rates were lower in younger children but increased with age.
Conclusion
Our systematic review highlights the crucial importance of providing allergen-sensitivity information that is specifically tailored to the local environment. This tailored approach can improve clinical diagnosis, enable appropriate allergen avoidance and immunotherapy strategies, and result in potential cost savings.
期刊介绍:
Clinical and Translational Allergy, one of several journals in the portfolio of the European Academy of Allergy and Clinical Immunology, provides a platform for the dissemination of allergy research and reviews, as well as EAACI position papers, task force reports and guidelines, amongst an international scientific audience.
Clinical and Translational Allergy accepts clinical and translational research in the following areas and other related topics: asthma, rhinitis, rhinosinusitis, drug hypersensitivity, allergic conjunctivitis, allergic skin diseases, atopic eczema, urticaria, angioedema, venom hypersensitivity, anaphylaxis, food allergy, immunotherapy, immune modulators and biologics, animal models of allergic disease, immune mechanisms, or any other topic related to allergic disease.