绿茶儿茶素:一种有希望的白血病抗癌方法。

IF 2.1 4区 医学 Q3 CHEMISTRY, MEDICINAL
Planta medica Pub Date : 2025-04-01 Epub Date: 2025-02-18 DOI:10.1055/a-2535-2003
Łukasz Mazur, Radosław Balwierz, Krzysztof Michalak, Wojciech Michalak, Agata Jasińska-Balwierz, Mariia Shanaida, Paweł Biernat, Tomasz Baj, Izabela Jasicka-Misiak
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引用次数: 0

摘要

绿茶儿茶素是一种具有生物活性的多酚类化合物,具有多种生物活性和潜在的健康益处。本文将重点讨论绿茶儿茶素的作用,并特别强调评估其抗癌潜力的临床研究。表没食子儿茶素没食子酸酯(EGCG),无论是单独治疗还是与常规抗癌疗法联合使用,都是白血病治疗的一种有希望的替代策略。本综述基于检索PubMed和Scopus数据库中检索的科学文献,检索关键词为:Camellia sinensis、tea儿茶素、抗癌、抗氧化、血液学癌症和白血病。深入了解其多方面的机制和研究结果,可以促进新策略的发展,并将绿茶儿茶素整合到临床实践中,从而提高白血病患者的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Green Tea Catechins: A Promising Anticancer Approach for Leukaemia.

Green tea catechins are bioactive polyphenolic compounds that possess a number of biological activities and potential health benefits. This review will focus on discussing the effects of green tea catechins, with a particular emphasis on clinical studies that evaluate their anticancer potential. Epigallocatechin gallate (EGCG), either as a stand-alone treatment or in conjunction with conventional anticancer therapies, represents a promising alternative strategy for the management of leukaemia. This review was based on a search of the scientific sources indexed in the databases PubMed and Scopus using the following keywords: 'Camellia sinensis', 'tea catechins', 'anticancer', 'antioxidant', 'hematological cancer', and 'leukaemia' in combination. A deeper comprehension of the multifaceted mechanisms and findings of research could facilitate the development of novel strategies and the integration of green tea catechins into clinical practice, thus enhancing treatment outcomes for patients with leukaemia.

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来源期刊
Planta medica
Planta medica 医学-药学
CiteScore
5.10
自引率
3.70%
发文量
101
审稿时长
1.8 months
期刊介绍: Planta Medica is one of the leading international journals in the field of natural products – including marine organisms, fungi as well as micro-organisms – and medicinal plants. Planta Medica accepts original research papers, reviews, minireviews and perspectives from researchers worldwide. The journal publishes 18 issues per year. The following areas of medicinal plants and natural product research are covered: -Biological and Pharmacological Activities -Natural Product Chemistry & Analytical Studies -Pharmacokinetic Investigations -Formulation and Delivery Systems of Natural Products. The journal explicitly encourages the submission of chemically characterized extracts.
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