普通人群的精神症状减轻:来自希腊观察性横断面ATTENTION研究的第一个数据。

IF 3.4 3区 医学 Q2 CLINICAL NEUROLOGY
Michaela Koummati, Jelena Vrublevska, Marc De Hert, Allan H Young, Paolo Fusar-Poli, Rajiv Tandon, Afzal Javed, Konstantinos N Fountoulakis
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引用次数: 0

摘要

背景:据报道,在一般“健康”人群中,异常经历可能是常见的,绝大多数人从未表现出明显的精神障碍。目的:本研究旨在量化一般人群的阈下精神症状。方法:该方案包括临床人口学数据和精神症状问卷,此外,还使用CES-D、STAI-S、RASS和GloDiS分别评估抑郁、焦虑、自杀倾向和功能障碍。数据在线匿名收集1504人(75.66%为女性;23.73%的男性)。采用描述性统计、风险比和因子分析。结果:临床抑郁症约占10%,躯体障碍占20.21%(两者均为9.90%),精神障碍史占42.75%。健康个体(占研究样本的46.94%)经历痛苦(8.6%)和阈下精神症状(精神病、分裂型不信任、情绪不稳定、从众、人际和社会功能减弱)。大约有10%的人出现轻度精神病症状,在40岁之前,转化为任何一种精神病的比率大约为每年0.5%,其中三分之一的人最终转化为精神病。超过40岁,似乎不会发生转变为精神病的情况。所有方面的症状都与功能障碍相关,但相关性较弱。结论:目前的研究结果与文献一致,并表明在普通人群中有相当数量的人经历了减轻的精神症状和轻度功能障碍,而从未表现出明显的精神障碍。有必要对这一问题进行进一步研究,以证实这些发现,并探讨其对身心健康和提供保健的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Attenuated mental symptoms in the general population: first data from the observational cross-sectional ATTENTION study in Greece.

Background: It has been reported that abnormal experiences could be common in the general "healthy" population, with the vast majority of individuals never proceeding to manifest a frank mental disorder.

Aims: This study aimed to quantify subthreshold psychiatric symptoms in the general population.

Methods: The protocol included clinicodemographic data and a mental symptoms questionnaire, and additionally, the CES-D, STAI-S, RASS, and the GloDiS to assess depression, anxiety, suicidality, and functional impairment, respectively. The data were collected online and anonymously from 1504 persons (75.66% females; 23.73% males). Descriptive statistics, risk ratios, and factor analysis were utilized.

Results: Clinical depression was present in approximately 10%, any somatic disorder in 20.21% (9.90% both), and a history of any mental disorder was present in 42.75%. The healthy individuals (46.94% of the study sample) were experiencing distress (8.6%) and subthreshold mental symptoms (attenuated psychotic, schizotypal distrust, emotional lability, conformity, and interpersonal and social functioning). Attenuated psychotic symptoms are present in almost 10%, and the conversion rate to any kind of psychosis was probably 0.5% per year until the age of 40, with one-third of these persons eventually converting. Beyond the age of 40, no conversion to psychosis seems to occur. All aspects of symptoms correlated weakly but significantly with aspects of functional impairment.

Conclusions: The results of the current study are in accord with the literature and suggest that a significant number of persons in the general population experience attenuated psychiatric symptoms and mild functional impairment without ever manifesting an overt mental disorder. There is a need for further research on this matter to confirm these findings and to explore their implications both for mental and somatic health and the provision of health care.

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来源期刊
CNS Spectrums
CNS Spectrums 医学-精神病学
CiteScore
6.20
自引率
6.10%
发文量
239
审稿时长
>12 weeks
期刊介绍: CNS Spectrums covers all aspects of the clinical neurosciences, neurotherapeutics, and neuropsychopharmacology, particularly those pertinent to the clinician and clinical investigator. The journal features focused, in-depth reviews, perspectives, and original research articles. New therapeutics of all types in psychiatry, mental health, and neurology are emphasized, especially first in man studies, proof of concept studies, and translational basic neuroscience studies. Subject coverage spans the full spectrum of neuropsychiatry, focusing on those crossing traditional boundaries between neurology and psychiatry.
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