通过科学、工程和工艺创新推进基于挤压的嵌入式3D生物打印。

IF 8.2 2区医学 Q1 ENGINEERING, BIOMEDICAL

Biofabrication Pub Date : 2025-03-10 DOI:10.1088/1758-5090/adb7c3

Ezgi Bakirci, Ali Asghari Adib, Syed Faaz Ashraf, Adam W Feinberg

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引用次数: 0

摘要

基于挤压的嵌入式3D生物打印技术，将生物墨水和生物材料挤压在支撑槽内，极大地扩展了可实现的组织结构和可制造的生物结构的复杂性。然而，要重建许多治疗应用所需的完整解剖结构和生理功能，仍然存在重大的科学、工程和工艺相关挑战。这一观点探讨了基于挤压的嵌入式3D生物打印的未来进展，可以解决这些挑战，为生物打印组织的临床转化铺平道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Advancing extrusion-based embedded 3D bioprinting via scientific, engineering, and process innovations.

Extrusion-based embedded 3D bioprinting, where bioinks and biomaterials are extruded within a support bath, has greatly expanded the achievable tissue architectures and complexity of biologic constructs that can be fabricated. However, significant scientific, engineering, and process-related challenges remain to recreate the full anatomic structure and physiologic function required for many therapeutic applications. This perspective explores the future advances in extrusion-based embedded 3D bioprinting that could address these challenges, paving the way for clinical translation of bioprinted tissues.

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来源期刊

Biofabrication ENGINEERING, BIOMEDICAL-MATERIALS SCIENCE, BIOMATERIALS

CiteScore

17.40

自引率

3.30%

发文量

118

审稿时长

2 months

期刊介绍： Biofabrication is dedicated to advancing cutting-edge research on the utilization of cells, proteins, biological materials, and biomaterials as fundamental components for the construction of biological systems and/or therapeutic products. Additionally, it proudly serves as the official journal of the International Society for Biofabrication (ISBF).