喀麦隆一家转诊医院缺血性中风患者的贫血和预后

Q3 Neuroscience

eNeurologicalSci Pub Date : 2025-02-14 DOI:10.1016/j.ensci.2025.100560

Yacouba Njankouo Mapoure , Elodie Dorothée Ebogo Fouda , Daniel Gams Massi , Caroline Kenmegne , Bertrand Hugo Ngahane Mbatchou

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引用次数: 0

摘要

中风和贫血是撒哈拉以南非洲的主要公共卫生问题。然而，在我们的环境中，很少有关于贫血和急性缺血性中风的数据。目的探讨贫血对缺血性脑卒中患者预后的影响。方法回顾性收集杜阿拉总医院住院15年的缺血性脑卒中患者9年的全血细胞计数资料。贫血分为轻度、中度和重度。采用多变量分析确定缺血性卒中合并贫血患者3个月预后不良（死亡率和功能恢复不良）的预测因素。结果共纳入691例男性患者，占53.3%。贫血占44.4%（重度贫血占10.4%）。重度贫血与3个月时功能恢复差显著相关（OR:4.43, 95% CI: 1.02-12.24, p = 0.04）。我们发现贫血患者（4.6%,n = 14）和非贫血患者（3.9%,n = 15） 3个月死亡率无差异（OR:1.48, 95% CI: 0.69-3.14, p = 0.330）。年龄比;60岁，舒张压；90 mmHg， NIHSS评分≥15，INR >；1.2是缺血性脑卒中合并贫血患者3个月死亡率的预测因素。结论贫血在缺血性脑卒中患者中较为常见，应系统筛查。

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Anemia and outcome of patients with ischemic stroke in a referral hospital in Cameroon

Background

Stroke and anemia are major public health concerns in Sub-Saharan Africa. However, few data are available on anemia and acute ischemic stroke in our setting.

Purpose

To assess the impact of anemia on the outcome of patients with ischemic stroke.

Methods

We collected retrospectively data of patients >15 years hospitalized for ischemic stroke at the Douala General Hospital over a period of 9 years, in whom full blood count was done. Anemia was classified as mild, moderate and severe. Multivariate analysis was used to determine predictive factors of poor outcome at 3 months (mortality and poor functional recovery) in ischemic stroke patients with anemia.

Results

A total of 691 patients (male, 53.3 %) male were included. Anemia was found in 44.4 % of cases (severe anemia, 10.4 %). Severe anemia was significantly associated with poor functional recovery at 3 months (OR:4.43, 95 %CI:1.02–12.24, p = 0.04). We found no difference in mortality at 3 months between patients with (4.6 %, n = 14) and without (3.9 %, n = 15) anemia (OR:1.48, 95 %CI:0.69–3.14, p = 0.330). Age > 60 years, diastolic blood pressure > 90 mmHg, NIHSS score ≥ 15, and INR > 1.2 were predictive factors of mortality at 3 months in ischemic stroke patients with anemia.

Conclusion

Anemia is common in ischemic stroke cases and must be systematically screened.

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来源期刊

eNeurologicalSci Neuroscience-Neurology

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

62 days

期刊介绍： eNeurologicalSci provides a medium for the prompt publication of original articles in neurology and neuroscience from around the world. eNS places special emphasis on articles that: 1) provide guidance to clinicians around the world (Best Practices, Global Neurology); 2) report cutting-edge science related to neurology (Basic and Translational Sciences); 3) educate readers about relevant and practical clinical outcomes in neurology (Outcomes Research); and 4) summarize or editorialize the current state of the literature (Reviews, Commentaries, and Editorials). eNS accepts most types of manuscripts for consideration including original research papers, short communications, reviews, book reviews, letters to the Editor, opinions and editorials. Topics considered will be from neurology-related fields that are of interest to practicing physicians around the world. Examples include neuromuscular diseases, demyelination, atrophies, dementia, neoplasms, infections, epilepsies, disturbances of consciousness, stroke and cerebral circulation, growth and development, plasticity and intermediary metabolism. The fields covered may include neuroanatomy, neurochemistry, neuroendocrinology, neuroepidemiology, neurogenetics, neuroimmunology, neuroophthalmology, neuropathology, neuropharmacology, neurophysiology, neuropsychology, neuroradiology, neurosurgery, neurooncology, neurotoxicology, restorative neurology, and tropical neurology.