类风湿关节炎研究和临床实践的进展要点。

IF 4.5 2区 医学 Q1 RHEUMATOLOGY
Jing He , Ajesh Basantharan Maharaj
{"title":"类风湿关节炎研究和临床实践的进展要点。","authors":"Jing He , Ajesh Basantharan Maharaj","doi":"10.1016/j.berh.2025.102040","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":50983,"journal":{"name":"Best Practice & Research in Clinical Rheumatology","volume":"39 1","pages":"Article 102040"},"PeriodicalIF":4.5000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Highlights of advancement in Rheumatoid Arthritis research and clinical practice\",\"authors\":\"Jing He , Ajesh Basantharan Maharaj\",\"doi\":\"10.1016/j.berh.2025.102040\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":50983,\"journal\":{\"name\":\"Best Practice & Research in Clinical Rheumatology\",\"volume\":\"39 1\",\"pages\":\"Article 102040\"},\"PeriodicalIF\":4.5000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Best Practice & Research in Clinical Rheumatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1521694225000087\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RHEUMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Best Practice & Research in Clinical Rheumatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1521694225000087","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

随着靶向治疗和国际治疗指南的出现,类风湿性关节炎的治疗也在不断发展。在“全球类风湿性关节炎治疗建议”中,Maharaj和他的同事比较了主要组织的方案,包括ACR(美国风湿病学会)、EULAR(欧洲风湿病协会联盟)和APLAR(亚太风湿病协会联盟)。他们分析了传统合成疾病缓解抗风湿药物(csDMARDs)、生物疾病缓解抗风湿药物(bDMARDs)和Janus激酶(JAK)抑制剂使用的地区差异。强调共同决策在解决保健差距方面的作用。然而,对于严重关节损伤或对药物治疗无反应的晚期疾病患者,手术方法仍然是治疗的关键组成部分。在“类风湿关节炎的关节置换术”中,Lü及其同事探讨了关节置换术技术和结果的适应症,特别是在缓解疼痛、功能恢复和生活质量方面。文章强调了手术技术和围手术期管理的进步,这些进步改善了患者的预后,同时降低了并发症的发生率。在个性化护理主题的基础上,他和同事在“治疗到目标的理论与实践”中讨论了治疗到目标(T2T)方法。该策略优先考虑通过持续监测和个体化治疗调整来实现缓解或低疾病活动度。这篇文章强调了生物治疗和严格评估工具的重要性,提出T2T是有效治疗RA的基石。这些药物、手术和个性化的方法形成了一个综合的框架,用于管理RA的临床范围。实现深度缓解仍然是类风湿性关节炎治疗的主要目标。在“类风湿性关节炎治疗的前景:从深度缓解到无药物”一文中,李铮和他的同事讨论了在患者达到持续缓解后停药的可行性。文章还评价了先进的成像技术,如超声和核磁共振成像,以监测疾病活动和指导治疗决策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Highlights of advancement in Rheumatoid Arthritis research and clinical practice
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
9.40
自引率
0.00%
发文量
43
审稿时长
27 days
期刊介绍: Evidence-based updates of best clinical practice across the spectrum of musculoskeletal conditions. Best Practice & Research: Clinical Rheumatology keeps the clinician or trainee informed of the latest developments and current recommended practice in the rapidly advancing fields of musculoskeletal conditions and science. The series provides a continuous update of current clinical practice. It is a topical serial publication that covers the spectrum of musculoskeletal conditions in a 4-year cycle. Each topic-based issue contains around 200 pages of practical, evidence-based review articles, which integrate the results from the latest original research with current clinical practice and thinking to provide a continuous update. Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. The review articles seek to address the clinical issues of diagnosis, treatment and patient management. Management is described in practical terms so that it can be applied to the individual patient. The serial is aimed at the physician in both practice and training.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信