儿童心脏病:炎症综合征

Q3 Medicine
FP essentials Pub Date : 2025-02-01
Craig Barstow, Ryan Flanagan
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引用次数: 0

摘要

川崎病是一种病因不明的急性血管炎,主要影响5岁以下儿童,但也可影响较大的儿童。心脏并发症是川崎病发病率和死亡率的主要原因,包括心肌炎。长期后遗症包括冠状动脉扩张。治疗是大剂量静脉注射免疫球蛋白和阿司匹林。儿童多系统炎症综合征(MIS-C)是一种与COVID-19疾病相关的严重高炎症综合征。它与川崎病有共同的临床特征,但引起过度炎症,并经常导致心功能障碍。misc的治疗是静脉注射免疫球蛋白和糖皮质激素。心肌炎是心肌和心包膜的炎症,有多种原因。它与COVID-19感染和mRNA COVID-19疫苗有关。这些关联的发生率和临床意义仍然不确定,是当前研究和辩论的主题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Heart Disease in Children: Inflammatory Syndromes.

Kawasaki disease is an acute vasculitis of unknown etiology that primarily affects children younger than 5 years, although it can affect older children. Cardiac complications are the major cause of morbidity and mortality in Kawasaki disease and can include myocarditis. Long-term sequelae include coronary artery dilation. Treatment is high-dose intravenous immunoglobulin and aspirin. Multisystem inflammatory syndrome in children (MIS-C) is a severe hyperinflammatory syndrome associated with COVID-19 disease. It shares clinical characteristics with Kawasaki disease but causes hyperinflammation and often results in cardiac dysfunction. Treatment for MIS-C is intravenous immunoglobulin and glucocorticoids. Myocarditis is inflammation of the myocardium and pericardium and has multiple causes. It is associated with COVID-19 infection and mRNA COVID-19 vaccines. The incidence and clinical significance of these associations remain uncertain and are a current topic of research and debate.

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FP essentials
FP essentials Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
58
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