Developing Behavior Change Model-Informed and Participant-Engaged Retention Strategies for Adolescents and Young Adults With Cancer Enrolled on Behavioral and/or Psychosocial Trials.

Adolescents and young adults (AYAs) with cancer face unique demands, which result in barriers to psychosocial/behavioral trial retention. Theory-informed and patient-engaged strategies have the potential to increase retention. The purpose of this manuscript is to illustrate how to partner with AYAs and leverage the Theoretical Domains Framework to identify barriers to retention and behavior change techniques (BCTs) targeting these barriers to create retention strategies. Exemplar strategies developed using this approach and implemented in our trial of an adherence-promotion intervention are discussed, and a roadmap is included for teams interested in developing similar strategies to meet their unique needs.