Ariadna Witte Castro, Maria Sanchez-Holgado, Miguel Saenz de Pipaon
{"title":"人乳中的生物活性化合物。","authors":"Ariadna Witte Castro, Maria Sanchez-Holgado, Miguel Saenz de Pipaon","doi":"10.1097/MCO.0000000000001114","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Human milk is the optimal food choice for infants. Reviewing the latest advances in research about human milk compounds and their effect on health helps understand the benefits of breastfeeding and improves knowledge of key bioactive nutrients that can be used to improve feeding during infancy, with short and long-time effects on health.</p><p><strong>Recent findings: </strong>In the last years, it has been described how bioactive compounds such as Human milk oligosaccharides, hormones, lipids, cellular components and microbes play an important role in the infants' health, reducing the risk of infectious, metabolic and autoimmune diseases. The mechanisms of transmission from the mother to the infant of these bioactive compounds are not always well described, but there are several lines of research to understand the biological mechanisms of these beneficial effects.</p><p><strong>Summary: </strong>These findings may help improve research in maternal and infant interventions, the modifiable factors that are able to modulate human milk composition. They may help to improve the development of infant formulas and enhance nutritional plans. Also, human milk bioactive compounds identification and isolation may describe new ways of supplementation.</p>","PeriodicalId":10962,"journal":{"name":"Current Opinion in Clinical Nutrition and Metabolic Care","volume":" ","pages":"243-249"},"PeriodicalIF":3.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bioactive compounds in human milk.\",\"authors\":\"Ariadna Witte Castro, Maria Sanchez-Holgado, Miguel Saenz de Pipaon\",\"doi\":\"10.1097/MCO.0000000000001114\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose of review: </strong>Human milk is the optimal food choice for infants. Reviewing the latest advances in research about human milk compounds and their effect on health helps understand the benefits of breastfeeding and improves knowledge of key bioactive nutrients that can be used to improve feeding during infancy, with short and long-time effects on health.</p><p><strong>Recent findings: </strong>In the last years, it has been described how bioactive compounds such as Human milk oligosaccharides, hormones, lipids, cellular components and microbes play an important role in the infants' health, reducing the risk of infectious, metabolic and autoimmune diseases. The mechanisms of transmission from the mother to the infant of these bioactive compounds are not always well described, but there are several lines of research to understand the biological mechanisms of these beneficial effects.</p><p><strong>Summary: </strong>These findings may help improve research in maternal and infant interventions, the modifiable factors that are able to modulate human milk composition. They may help to improve the development of infant formulas and enhance nutritional plans. Also, human milk bioactive compounds identification and isolation may describe new ways of supplementation.</p>\",\"PeriodicalId\":10962,\"journal\":{\"name\":\"Current Opinion in Clinical Nutrition and Metabolic Care\",\"volume\":\" \",\"pages\":\"243-249\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Clinical Nutrition and Metabolic Care\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/MCO.0000000000001114\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/12 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Clinical Nutrition and Metabolic Care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MCO.0000000000001114","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/12 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Purpose of review: Human milk is the optimal food choice for infants. Reviewing the latest advances in research about human milk compounds and their effect on health helps understand the benefits of breastfeeding and improves knowledge of key bioactive nutrients that can be used to improve feeding during infancy, with short and long-time effects on health.
Recent findings: In the last years, it has been described how bioactive compounds such as Human milk oligosaccharides, hormones, lipids, cellular components and microbes play an important role in the infants' health, reducing the risk of infectious, metabolic and autoimmune diseases. The mechanisms of transmission from the mother to the infant of these bioactive compounds are not always well described, but there are several lines of research to understand the biological mechanisms of these beneficial effects.
Summary: These findings may help improve research in maternal and infant interventions, the modifiable factors that are able to modulate human milk composition. They may help to improve the development of infant formulas and enhance nutritional plans. Also, human milk bioactive compounds identification and isolation may describe new ways of supplementation.
期刊介绍：
A high impact review journal which boasts an international readership, Current Opinion in Clinical Nutrition and Metabolic Care offers a broad-based perspective on the most recent and exciting developments within the field of clinical nutrition and metabolic care. Published bimonthly, each issue features insightful editorials and high quality invited reviews covering two or three key disciplines which include protein, amino acid metabolism and therapy, lipid metabolism and therapy, nutrition and the intensive care unit and carbohydrates. Each discipline introduces world renowned guest editors to ensure the journal is at the forefront of knowledge development and delivers balanced, expert assessments of advances from the previous year.
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