Dongfang Liu, Liqin Huang, Yu Jing, Tingmei Huang, Di Zhang, Dong Jiang, Yaxin Zhao and Yuanyuan Zhang
{"title":"水杨酸诱导从蠕虫样胶束形成超分子抗菌水凝胶。","authors":"Dongfang Liu, Liqin Huang, Yu Jing, Tingmei Huang, Di Zhang, Dong Jiang, Yaxin Zhao and Yuanyuan Zhang","doi":"10.1039/D4SM01411A","DOIUrl":null,"url":null,"abstract":"<p >The incorporation of salicylic acid (SA) facilitates the gelation of worm-like micelles (WLMs) derived from sodium lauroyl glutamate (LGS) and cetyltrimethylammonium bromide (CTAB) under acidic conditions, thereby constructing a pH-responsive supramolecular hydrogel system. SA significantly enhances the transition from WLMs to the gel state, as evidenced by changes in the storage modulus (<em>G</em>′) and loss modulus (<em>G</em>′′), highlighting its pivotal role in dynamic network crosslinking. The electrostatic interaction between CTAB and LGS provides a foundation for the formation of the LGS/CTAB/SA hydrogel. This study further elucidates the sustained release and antibacterial properties of SA as a drug molecule and assesses the antibacterial capabilities of various hydrogel formulations, thereby providing a robust theoretical and experimental foundation for the development of novel multifunctional supramolecular hydrogels.</p>","PeriodicalId":103,"journal":{"name":"Soft Matter","volume":" 10","pages":" 1915-1924"},"PeriodicalIF":2.8000,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Salicylic acid induces the formation of supramolecular antimicrobial hydrogels from worm-like micelles†\",\"authors\":\"Dongfang Liu, Liqin Huang, Yu Jing, Tingmei Huang, Di Zhang, Dong Jiang, Yaxin Zhao and Yuanyuan Zhang\",\"doi\":\"10.1039/D4SM01411A\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >The incorporation of salicylic acid (SA) facilitates the gelation of worm-like micelles (WLMs) derived from sodium lauroyl glutamate (LGS) and cetyltrimethylammonium bromide (CTAB) under acidic conditions, thereby constructing a pH-responsive supramolecular hydrogel system. SA significantly enhances the transition from WLMs to the gel state, as evidenced by changes in the storage modulus (<em>G</em>′) and loss modulus (<em>G</em>′′), highlighting its pivotal role in dynamic network crosslinking. The electrostatic interaction between CTAB and LGS provides a foundation for the formation of the LGS/CTAB/SA hydrogel. This study further elucidates the sustained release and antibacterial properties of SA as a drug molecule and assesses the antibacterial capabilities of various hydrogel formulations, thereby providing a robust theoretical and experimental foundation for the development of novel multifunctional supramolecular hydrogels.</p>\",\"PeriodicalId\":103,\"journal\":{\"name\":\"Soft Matter\",\"volume\":\" 10\",\"pages\":\" 1915-1924\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-01-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Soft Matter\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://pubs.rsc.org/en/content/articlelanding/2025/sm/d4sm01411a\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Soft Matter","FirstCategoryId":"92","ListUrlMain":"https://pubs.rsc.org/en/content/articlelanding/2025/sm/d4sm01411a","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Salicylic acid induces the formation of supramolecular antimicrobial hydrogels from worm-like micelles†
The incorporation of salicylic acid (SA) facilitates the gelation of worm-like micelles (WLMs) derived from sodium lauroyl glutamate (LGS) and cetyltrimethylammonium bromide (CTAB) under acidic conditions, thereby constructing a pH-responsive supramolecular hydrogel system. SA significantly enhances the transition from WLMs to the gel state, as evidenced by changes in the storage modulus (G′) and loss modulus (G′′), highlighting its pivotal role in dynamic network crosslinking. The electrostatic interaction between CTAB and LGS provides a foundation for the formation of the LGS/CTAB/SA hydrogel. This study further elucidates the sustained release and antibacterial properties of SA as a drug molecule and assesses the antibacterial capabilities of various hydrogel formulations, thereby providing a robust theoretical and experimental foundation for the development of novel multifunctional supramolecular hydrogels.
期刊介绍:
Soft Matter is an international journal published by the Royal Society of Chemistry using Engineering-Materials Science: A Synthesis as its research focus. It publishes original research articles, review articles, and synthesis articles related to this field, reporting the latest discoveries in the relevant theoretical, practical, and applied disciplines in a timely manner, and aims to promote the rapid exchange of scientific information in this subject area. The journal is an open access journal. The journal is an open access journal and has not been placed on the alert list in the last three years.