水杨酸诱导从蠕虫样胶束形成超分子抗菌水凝胶。

IF 2.8 3区 化学 Q3 CHEMISTRY, PHYSICAL
Soft Matter Pub Date : 2025-01-25 DOI:10.1039/D4SM01411A
Dongfang Liu, Liqin Huang, Yu Jing, Tingmei Huang, Di Zhang, Dong Jiang, Yaxin Zhao and Yuanyuan Zhang
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引用次数: 0

摘要

水杨酸(SA)的掺入促进了月桂酰谷氨酸钠(LGS)和十六烷基三甲基溴化铵(CTAB)衍生的蠕虫状胶束(WLMs)在酸性条件下的凝胶化,从而构建了ph响应的超分子水凝胶体系。SA显著增强了wlm向凝胶态的转变,其存储模量(G’)和损耗模量(G’)的变化证明了SA在动态网络交联中的关键作用。CTAB与LGS之间的静电相互作用为LGS/CTAB/SA水凝胶的形成提供了基础。本研究进一步阐明了SA作为药物分子的缓释和抗菌特性,并对不同水凝胶配方的抗菌性能进行了评价,从而为开发新型多功能超分子水凝胶提供了坚实的理论和实验基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Salicylic acid induces the formation of supramolecular antimicrobial hydrogels from worm-like micelles†

Salicylic acid induces the formation of supramolecular antimicrobial hydrogels from worm-like micelles†

The incorporation of salicylic acid (SA) facilitates the gelation of worm-like micelles (WLMs) derived from sodium lauroyl glutamate (LGS) and cetyltrimethylammonium bromide (CTAB) under acidic conditions, thereby constructing a pH-responsive supramolecular hydrogel system. SA significantly enhances the transition from WLMs to the gel state, as evidenced by changes in the storage modulus (G′) and loss modulus (G′′), highlighting its pivotal role in dynamic network crosslinking. The electrostatic interaction between CTAB and LGS provides a foundation for the formation of the LGS/CTAB/SA hydrogel. This study further elucidates the sustained release and antibacterial properties of SA as a drug molecule and assesses the antibacterial capabilities of various hydrogel formulations, thereby providing a robust theoretical and experimental foundation for the development of novel multifunctional supramolecular hydrogels.

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来源期刊
Soft Matter
Soft Matter 工程技术-材料科学:综合
CiteScore
6.00
自引率
5.90%
发文量
891
审稿时长
1.9 months
期刊介绍: Soft Matter is an international journal published by the Royal Society of Chemistry using Engineering-Materials Science: A Synthesis as its research focus. It publishes original research articles, review articles, and synthesis articles related to this field, reporting the latest discoveries in the relevant theoretical, practical, and applied disciplines in a timely manner, and aims to promote the rapid exchange of scientific information in this subject area. The journal is an open access journal. The journal is an open access journal and has not been placed on the alert list in the last three years.
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