Daniela Luethy, Catalina Cabrera, Lisette M. Coll-Roman, Ashley R. VanderBroek, Sarah M. Depenbrock, Anje G. Bauck, Audrey A. Kelleman, Jenna W. Stockler, Clare Scully, Caitlin Wiley, Evelyn E. Mackay, Michelle Abraham, Laurence Leduc, Charlene V. Noll, Marie-Eve Fecteau, Laurel E. Redding
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Redding","doi":"10.1111/jvim.70005","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Understanding antimicrobial use practices in goats is essential to ensuring appropriate antimicrobial stewardship.</p>\n </section>\n \n <section>\n \n <h3> Objective</h3>\n \n <p>To describe antimicrobial prescriptions in periparturient does admitted to veterinary teaching hospitals and to determine if any factors were associated with the administration of antimicrobials in general or ceftiofur in particular.</p>\n </section>\n \n <section>\n \n <h3> Animals</h3>\n \n <p>One hundred ninety-eight periparturient does presented to nine university veterinary hospitals from October 2021 to June 2022.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A multicenter cross-sectional study in a prospective design. Data were collected from questionnaire completed by admitting clinician.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Out of 198 periparturient does included in the study, 153 (77%) received antimicrobials during hospitalization. Commonly administered antimicrobials included oxytetracycline (<i>n</i> = 44, 29%), ceftiofur sodium (<i>n</i> = 43, 28%), ceftiofur crystalline free acid (CCFA; <i>n</i> = 27, 18%), potassium penicillin G (<i>n</i> = 15, 10%), procaine penicillin G (<i>n</i> = 14, 9%), florfenicol (<i>n</i> = 14, 9%), tulathromycin (<i>n</i> = 9, 6%), ampicillin trihydrate (<i>n</i> = 4, 3%), and ampicillin sodium (<i>n</i> = 1, 1%). Cesarean section was associated with antimicrobial administration in general (OR = 5.89; 95% CI = 2.49–13.98, <i>p</i> < 0.01) and with ceftiofur administration (OR = 2.54, 95% CI = 1.25–5.17; <i>p</i> = 0.008). Significant variability in ceftiofur administration by hospital was observed (<i>p</i> < 0.001).</p>\n </section>\n \n <section>\n \n <h3> Conclusions and Clinical Importance</h3>\n \n <p>Marked heterogeneity was observed in the antimicrobial administration practices in periparturient goats between nine US veterinary teaching hospitals.</p>\n </section>\n </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 2","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70005","citationCount":"0","resultStr":"{\"title\":\"Antimicrobial Administration Practices in Hospitalized Periparturient Goats: A Multicenter Study\",\"authors\":\"Daniela Luethy, Catalina Cabrera, Lisette M. Coll-Roman, Ashley R. VanderBroek, Sarah M. Depenbrock, Anje G. Bauck, Audrey A. Kelleman, Jenna W. 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Antimicrobial Administration Practices in Hospitalized Periparturient Goats: A Multicenter Study
Background
Understanding antimicrobial use practices in goats is essential to ensuring appropriate antimicrobial stewardship.
Objective
To describe antimicrobial prescriptions in periparturient does admitted to veterinary teaching hospitals and to determine if any factors were associated with the administration of antimicrobials in general or ceftiofur in particular.
Animals
One hundred ninety-eight periparturient does presented to nine university veterinary hospitals from October 2021 to June 2022.
Methods
A multicenter cross-sectional study in a prospective design. Data were collected from questionnaire completed by admitting clinician.
Results
Out of 198 periparturient does included in the study, 153 (77%) received antimicrobials during hospitalization. Commonly administered antimicrobials included oxytetracycline (n = 44, 29%), ceftiofur sodium (n = 43, 28%), ceftiofur crystalline free acid (CCFA; n = 27, 18%), potassium penicillin G (n = 15, 10%), procaine penicillin G (n = 14, 9%), florfenicol (n = 14, 9%), tulathromycin (n = 9, 6%), ampicillin trihydrate (n = 4, 3%), and ampicillin sodium (n = 1, 1%). Cesarean section was associated with antimicrobial administration in general (OR = 5.89; 95% CI = 2.49–13.98, p < 0.01) and with ceftiofur administration (OR = 2.54, 95% CI = 1.25–5.17; p = 0.008). Significant variability in ceftiofur administration by hospital was observed (p < 0.001).
Conclusions and Clinical Importance
Marked heterogeneity was observed in the antimicrobial administration practices in periparturient goats between nine US veterinary teaching hospitals.
期刊介绍：
The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.
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