低肌肉减少指数预测腹部外伤患者的腹腔感染

IF 3.2 3区医学 Q2 NUTRITION & DIETETICS

Nutrition Pub Date : 2025-02-01 DOI:10.1016/j.nut.2025.112695

Fengchan Xi M.D., Ph.D. , Ran Teng M.D. , Bing Xiong M.D. , Di Wang M.D. , Nan Zheng M.D. , Jinghui Cheng M.D. , Wei Dong B.S. , Xinwei Huang B.S. , Xiling Wang Ph.D. , Shanjun Tan M.D., Ph.D.

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引用次数: 0

摘要

目的预测腹部外伤患者的腹腔内感染（IAI）至关重要，但目前缺乏可靠的预测指标。肌少症指数（SI）是几种疾病的临床结果的现成指标，具有诊断和预后价值。本研究的目的是评估SI对腹部创伤患者IAI的预测价值。方法回顾性队列研究纳入腹部创伤患者。采用多变量logistic分析确定影响IAI的独立因素。我们根据性别将患者分为两组。采用受试者工作特征（ROC）曲线评价SI预测IAI的效果。然后，根据男性和女性SI的临界值，我们将患者分为高iai和低iai风险组，比较临床结果。相关性分析采用Spearman相关分析。结果共纳入378例腹部外伤患者。多变量logistic分析确定SI是两名男性IAI的独立危险因素[优势比（OR）： 0.82, 95%可信区间（CI）： 0.74-0.90, P <；0.001]和女性（OR: 0.68, 95% CI: 0.51-0.91, P = 0.009）。SI预测IAI的ROC曲线下面积男性为0.712，女性为0.733，最佳截断值男性为81.430，女性为57.907。此外，SI与住院时间（P = 0.003）和住院费用（P = 0.042）呈显著相关。结论si是腹部外伤患者IAI的独立危险因素，对男女患者均有预测价值。SI与不良临床结果相关。这可能为IAI的诊断和治疗提供新的思路和理论指导。

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Low sarcopenia index predicts intra-abdominal infection in patients with abdominal trauma

Objectives

Prediction of intra-abdominal infection (IAI) in patients with abdominal trauma is crucial, yet reliable predictive indicators are currently lacking. The sarcopenia index (SI) is a readily available indicator of clinical outcomes in several diseases that holds diagnostic and prognostic value. The aim of this study is to assess the predictive value of SI for IAI in patients with abdominal trauma.

Methods

This retrospective cohort study enrolled patients with abdominal trauma. Multivariable logistic analyses were used to identify independent factors of IAI. We divided patients into 2 groups based on sex. The receiver operating characteristic (ROC) curve was used to evaluate the performance of SI in predicting IAI. Then, based on the cut-off values of the SI established for males and females, we stratified patients into high and low-IAI risk groups to compare clinical outcomes. Spearman correlation analysis was used for correlation analysis.

Results

A total of 378 participants with abdominal trauma were included. Multivariable logistic analyses identified SI as an independent risk factor for IAI in both males [odds ratio (OR): 0.82, 95% confidence interval (CI): 0.74-0.90, P < 0.001] and females (OR: 0.68, 95% CI: 0.51-0.91, P = 0.009). The area under the ROC curve for SI in predicting IAI was 0.712 for males and 0.733 for females, with optimal cut-off values of 81.430 for males and 57.907 for females. Furthermore, SI showed significant correlations with the length of hospital stay (P = 0.003) and hospital costs (P = 0.042).

Conclusions

SI was identified as an independent risk factor for IAI in patients with abdominal trauma, offering predictive value for both genders. SI correlates with poor clinical outcomes. This might provide new ideas and theoretical guidance for diagnosing and treating IAI.

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来源期刊

Nutrition 医学-营养学

CiteScore

7.80

自引率

2.30%

发文量

300

审稿时长

60 days

期刊介绍： Nutrition has an open access mirror journal Nutrition: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Founded by Michael M. Meguid in the early 1980''s, Nutrition presents advances in nutrition research and science, informs its readers on new and advancing technologies and data in clinical nutrition practice, encourages the application of outcomes research and meta-analyses to problems in patient-related nutrition; and seeks to help clarify and set the research, policy and practice agenda for nutrition science to enhance human well-being in the years ahead.