导管内乳头状粘液腺癌合并梗阻性胰腺炎根治性切除1例

Q4 Medicine
Kenji Sakai, Kunihito Gotoh, Naoki Hama, Reishi Toshiyama, Mao Osaki, Shinji Tokuyama, Masaaki Yamamoto, Kenji Kawai, Yusuke Takahashi, Atushi Takeno, Takeshi Kato, Motohiro Hirao
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引用次数: 0

摘要

我们报告一例IPMC合并梗阻性胰腺炎由于十二指肠穿孔,其中进行根治性手术。患者是一名50岁的男性。他被转介到他以前的医生那里做了一次彻底的黄疸和肝损伤检查。ERCP显示肿瘤暴露于十二指肠球部,怀疑为IPMC,但活检未见恶性结果。患者因梗阻性胰腺炎接受治疗,但炎症反应仍然升高。影像学检查显示胰腺体尾周围仍有炎症,门静脉周围炎症较轻。胰十二指肠切除术时胃大部保留。病理结果显示诊断为IPMC,由于可压缩性导管内肿瘤生长而破坏十二指肠壁,并伴有大面积急性炎症。患者接受S-1辅助术后化疗6个月,目前无复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[A Case of Radical Resection of Intraductal Papillary Mucinous Adenocarcinoma Complicated by Obstructive Pancreatitis].

We report a case of IPMC complicated with obstructive pancreatitis due to perforation of the duodenum, in which radical surgery was performed. The patient was a 50-year-old man. He was referred to his previous doctor for a thorough examination of jaundice and liver damage. ERCP showed a tumour exposed in the duodenal bulb and IPMC was suspected, but biopsy showed no malignant findings. The patient was treated for obstructive pancreatitis, but the inflammatory response remained elevated. On imaging evaluation, inflammation around the pancreatic body tail remained, but inflammation around the portal vein was relatively mild. The pancreaticoduodenectomy was performed with sub-total gastric preservation. The pathology results showed a diagnosis of IPMC, with destruction of the duodenal wall due to compressible intraductal tumour growth, and a wide area of acute inflammation. The patient was treated with S-1 as adjuvant post-operative chemotherapy for 6 months and is currently recurrence-free.

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