用于神经外科的微创共径OCT系统。

IF 2.9 2区医学 Q2 BIOCHEMICAL RESEARCH METHODS

Biomedical optics express Pub Date : 2025-01-31 eCollection Date: 2025-02-01 DOI:10.1364/BOE.549160

Gary Evans, Jerome Gandar, Simon Thiele, David J Segar, Yoseline Rosales Cabara, Matthew Lapinski, Ivana Gantar, Thierry Campiche, Corinne Brana, Michalina J Gora, Jules Scholler

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引用次数: 0

摘要

我们提出了一种微创共路光学相干断层扫描（OCT）系统，该系统工作在1310纳米，具有新颖的前视单片内窥镜，专为具有实时3D成像功能的神经外科应用而设计。该系统的实时组织识别能力可以提高立体定向手术的准确性，包括深部脑刺激和活检，而其检测血流的能力可以显著降低出血的风险。该系统已成功地在兔群体内进行了测试。

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Minimally-invasive common-path OCT system for neurosurgery applications.

We present a minimally-invasive common-path optical coherence tomography (OCT) system operating at 1310 nm with a novel forward viewing monolithic endoscope designed specifically for neurosurgical applications with real-time 3D imaging capabilities. This system's real-time tissue identification capability could enhance the accuracy of stereotactic surgeries, including deep brain stimulation and biopsy, while its ability to detect blood flow could significantly reduce the risk of hemorrhage. The system was successfully tested in vivo in a rabbit cohort.

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来源期刊

Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS

CiteScore

6.80

自引率

11.80%

发文量

633

审稿时长

1 months

期刊介绍： The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.