{"title":"可行性采用紧凑型光纤Sagnac干涉仪进行非接触式软组织表面机械波速度检测。","authors":"Gui Chen, Jinjun Xia","doi":"10.1364/BOE.534396","DOIUrl":null,"url":null,"abstract":"<p><p>The Sagnac interferometer offers distinct advantages in vibrational wave detection. In this study, an air-coupled transducer and a compact fiber-optic Sagnac interferometer were developed for non-contact elasticity characterization in biological tissues. Given the challenge of limited light collection by a compact fiber optic Sagnac interferometer in biological tissues, this study aims to explore the potential of using a compact Sagnac interferometer to measure vibrational waves in biological tissues. The speeds of the generated vibrational surface waves in tissue-mimic phantoms were measured. Measurement errors caused by cross-correlation wave tracking were analyzed, and the performance of the integrated system was characterized. The results demonstrated the effectiveness of the integrated system and the cross-correlation algorithm in tracing the speed of vibrational surface waves in tissue-mimicking phantoms. They suggested potential applications for the non-invasive, contactless characterization of the mechanical properties in soft biological tissues.</p>","PeriodicalId":8969,"journal":{"name":"Biomedical optics express","volume":"16 2","pages":"603-616"},"PeriodicalIF":2.9000,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11828435/pdf/","citationCount":"0","resultStr":"{\"title\":\"Feasibility using a compact fiber optic Sagnac interferometer for non-contact soft tissue surface mechanical wave speed detection.\",\"authors\":\"Gui Chen, Jinjun Xia\",\"doi\":\"10.1364/BOE.534396\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Sagnac interferometer offers distinct advantages in vibrational wave detection. In this study, an air-coupled transducer and a compact fiber-optic Sagnac interferometer were developed for non-contact elasticity characterization in biological tissues. Given the challenge of limited light collection by a compact fiber optic Sagnac interferometer in biological tissues, this study aims to explore the potential of using a compact Sagnac interferometer to measure vibrational waves in biological tissues. The speeds of the generated vibrational surface waves in tissue-mimic phantoms were measured. Measurement errors caused by cross-correlation wave tracking were analyzed, and the performance of the integrated system was characterized. The results demonstrated the effectiveness of the integrated system and the cross-correlation algorithm in tracing the speed of vibrational surface waves in tissue-mimicking phantoms. They suggested potential applications for the non-invasive, contactless characterization of the mechanical properties in soft biological tissues.</p>\",\"PeriodicalId\":8969,\"journal\":{\"name\":\"Biomedical optics express\",\"volume\":\"16 2\",\"pages\":\"603-616\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-01-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11828435/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomedical optics express\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1364/BOE.534396\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical optics express","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1364/BOE.534396","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Feasibility using a compact fiber optic Sagnac interferometer for non-contact soft tissue surface mechanical wave speed detection.
The Sagnac interferometer offers distinct advantages in vibrational wave detection. In this study, an air-coupled transducer and a compact fiber-optic Sagnac interferometer were developed for non-contact elasticity characterization in biological tissues. Given the challenge of limited light collection by a compact fiber optic Sagnac interferometer in biological tissues, this study aims to explore the potential of using a compact Sagnac interferometer to measure vibrational waves in biological tissues. The speeds of the generated vibrational surface waves in tissue-mimic phantoms were measured. Measurement errors caused by cross-correlation wave tracking were analyzed, and the performance of the integrated system was characterized. The results demonstrated the effectiveness of the integrated system and the cross-correlation algorithm in tracing the speed of vibrational surface waves in tissue-mimicking phantoms. They suggested potential applications for the non-invasive, contactless characterization of the mechanical properties in soft biological tissues.
期刊介绍:
The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including:
Tissue optics and spectroscopy
Novel microscopies
Optical coherence tomography
Diffuse and fluorescence tomography
Photoacoustic and multimodal imaging
Molecular imaging and therapies
Nanophotonic biosensing
Optical biophysics/photobiology
Microfluidic optical devices
Vision research.